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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C42H82NO8P
CAS 번호:
Molecular Weight:
760.08
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
description
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (850457P-1g), pkg of 2 × 100 mg (850457P-200mg), pkg of 5 × 100 mg (850457P-500mg), pkg of 1 × 25 mg (850457P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI key
WTJKGGKOPKCXLL-VYOBOKEXSA-N
General description
POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
Application
16:0-18:1 PC has been used in the preparation of liposomes for the muramyl tripeptide encapsulation. It has also been used in the preparation of membrane scaffold protein 1 nanodisc. 16:0-18:1 PC may be used in the synthesis of discoidal reconstituted high-density lipoproteins.
Biochem/physiol Actions
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)or 16:0-18:1 PC plays an important role as a lung surfactant and reduces surface tension. POPC mimics natural cell membrane and may be useful for unsaturated lipids oxidation studies. Its interaction with ozone leads to oxidative decomposition at the oleoyl strand C-C moiety.
Packaging
5 mL Clear Glass Sealed Ampule (850457P-200mg)
5 mL Clear Glass Sealed Ampule (850457P-25mg)
5 mL Clear Glass Sealed Ampule (850457P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850457P-1g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Modified apolipoprotein (apo) AI by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state
Jang W, et al.
Molecules and Cells, 31(5), 461-470 (2011)
Oxidative degradation of the monolayer of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) in low-level ozone
Qiao L, et al.
The Journal of Physical Chemistry B, 119(44), 14188-14199 (2015)
Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 850457P-1G | 04061835230860 |
| 850457P-200MG | 04061835230877 |
| 850457P-25MG | 04061835230884 |
| 850457P-500MG | 04061835230891 |