description
1,2-distearoyl-sn-glycero-3-phosphocholine
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (850365P-1G), pkg of 1 × 200 mg (850365P-200MG), pkg of 1 × 25 mg (850365P-25MG), pkg of 1 × 500 mg (850365P-500MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
InChI
1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
InChI key
NRJAVPSFFCBXDT-HUESYALOSA-N
General description
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phospholtidylcholine with alkyl chain comprising 18 carbons. It has phophatidylcholine head group and its structure is similar to 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC).
Application
18:0 PC (DSPC) has been used:
- in the microbubble monolayer preparation for biomolecule delivery studies into protoplasts
- in the preparation of liposomes for immobilization studies
- in the generation of porphyrin-phospholipid (PoP) liposomes for irinotecan (IRT) and doxorubicin delivery
Biochem/physiol Actions
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is used in combination with other members of phosphatidylcholine for the generation of mixed bilayer system. It is majorly used in conventional and stealth liposome preparation for drug delivery studies.
Packaging
20 mL Clear Glass Screw Cap Vial (850365P-1G)
20 mL Clear Glass Screw Cap Vial (850365P-500MG)
5 mL Amber Glass Screw Cap Vial (850365P-200MG)
5 mL Amber Glass Screw Cap Vial (850365P-25MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Investigating the structure of multicomponent gel-phase lipid bilayers
Hartkamp R, et al.
Biophysical Journal, 111(4), 813-823 (2016)
Comparative study of PEGylated and conventional liposomes as carriers for shikonin
Tsermentseli S, et al.
Fluids, 3(2), 36-36 (2018)
A coarse-grained molecular dynamics study of DLPC, DMPC, DPPC, and DSPC mixtures in aqueous solution
Abedi K, et al.
Journal of Chemistry, 2013 (2013)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 850365P-1G | 04061835230471 |
| 850365P-200MG | 04061835230488 |
| 850365P-25MG | 04061835230495 |
| 850365P-500MG | 04061835230501 |
| 850365P-5G | 04065273778410 |