assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g, pkg of 1 × 5 g
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C(CCCCCCCCCCCCC)OCC(OC(CCCCCCCCCCCCC)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
InChI key
NLDCRRFPGOSAHV-UHFFFAOYSA-N
General description
Structure, molecular formula and formula weight are representative of the average polymer length of the material.
Dimyristoyl glycerol (DMG) molecule associates with membrane similar to phospholipids.
Application
DMG-PEG 2000 is suitable for use in the preparation of lipid nanoparticle for microRNA and short interfering RNA delivery.
Biochem/physiol Actions
Dimyristoyl glycerol (DMG) − polyethyleneglycol (PEG) 2000 is used for liposome preparation for anticancer drug delivery studies for hepatocellular, gastrointestinal, neuroendocrine and adrenocortical carcinoma. It is also used in lipid nanoparticle preparation for siRNA (small interfering RNA) delivery.
Packaging
20 mL Clear Glass Screw Cap Vial (880151P-1G)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (880151P-5G)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (880151P-5G)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Liver-Specific silencing of Lipin1 reduces fat mass as well as hepatic triglyceride biosynthesis in mice
Kajimoto K, et al.
Biological & Pharmaceutical Bulletin, 39(10), 1653-1661 (2016)
Dynamic chain conformations in dimyristoyl glycerol-dimyristoyl phosphatidylcholine mixtures. 2H-NMR studies
Schorn K and Marsh D
Biophysical Journal, 71(6), 3320-3329 (1996)
Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia
Huang X, et al.
Clinical Cancer Research, 19(9), 2355-2367 (2013)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 880151P-1G | 04061838814241 |
| 880151P-5G | 04061838814258 |