조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C42H80NO4Cl
CAS 번호:
Molecular Weight:
698.54
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g ((890890P-1G)), pkg of 2 × 100 mg ((890890P-200MG)), pkg of 5 × 100 mg ((890890P-100MG)), pkg of 1 × 25 mg ((890890P-25MG))
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
advanced drug delivery
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]
InChI
1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
InChI key
KSXTUUUQYQYKCR-LQDDAWAPSA-M
Application
18:1 TAP (DOTAP) has been used in chloroform solutions to form dry film in the preparation of cationic liposomes. It has also been used in standard stock solution used for the preparation of cationic liposomes.
Biochem/physiol Actions
DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).
Packaging
5 mL Clear Glass Sealed Ampule (890890P-200mg)
5 mL Clear Glass Sealed Ampule (890890P-25mg)
5 mL Clear Glass Sealed Ampule (890890P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (890890P-1g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis
Li Y, et al.
BMC Pharmacology & Toxicology, 19(1), 43-43 (2018)
Efficient siRNA delivery by the cationic liposome DOTAP in human hematopoietic stem cells differentiating into dendritic cells
Martino S, et al.
BioMed Research International, 2009 (2009)
DOTAP (and other cationic lipids): chemistry, biophysics, and transfection
Simberg D, et al.
Critical Reviews in Therapeutic Drug Carrier Systems, 21(4) (2004)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 890890P-500MG | 04061835188543 |
| 890890P-1G | 04061835188512 |
| 890890P-200MG | 04061835188529 |
| 890890P-25MG | 04061835188536 |