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Merck

860678P

Avanti

C24 Ceramide-d7 (d18:1-d7/24:0)

Avanti Research - A Croda Brand

동의어(들):

N-lignoceroyl-D-erythro-sphingosine (d7)

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C42H76D7NO3
CAS 번호:
Molecular Weight:
657.16
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352100
Assay:
>99% (TLC)
Form:
powder
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제품 이름

C24 Ceramide-d7 (d18:1-d7/24:0), Avanti Research - A Croda Brand 860678P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860678P-1mg), pkg of 1 × 5 mg (860678P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860678P

shipped in

dry ice

storage temp.

−20°C

General description

C24 Ceramide (d18:1/24:0) is a synthetic ceramide containing sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide. C24 Ceramide-d7 (d18:1-d7/24:0) is a deuterated derivative of C24 Ceramide (d18:1/24:0).

Application

C24 Ceramide-d7 (d18:1-d7/24:0) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24 ceramide in skeletal muscle.

Biochem/physiol Actions

C24 Ceramide plays a vital role in inducing cell death. Altered levels of C24 ceramide might be a potential indication in tumor monitoring. Determining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma helps to predict fatal outcome of coronary artery disease. The stable isotope form of C24 Ceramide (d18:1/24:0) is convenient for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860678P-1mg)
5 mL Amber Glass Screw Cap Vial (860678P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문



Yenisleidy de Las Mercedes Zulueta Díaz et al.
Colloids and surfaces. B, Biointerfaces, 185, 110621-110621 (2019-11-15)
L-ascorbic acid alkyl esters (ASCn) are lipophilic forms of vitamin C, which act as skin permeation enhancers. We investigated the physical changes induced by incorporating ASCn into stratum corneum (SC) lipid membranes and correlated this with the mechanism proposed in
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the



국제 무역 품목 번호

SKUGTIN
860678P-1MG04061835186686