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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C34H60D7NO3
CAS 번호:
Molecular Weight:
544.94
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.12
Assay:
>99% (TLC)
Form:
powder
제품 이름
C16 Ceramide-d7 (d18:1-d7/16:0), Avanti Research™ - A Croda Brand 860676P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860676P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860676P
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
InChI
1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1/i1D3,3D2,5D2
InChI key
YDNKGFDKKRUKPY-HJSOYJPBSA-N
General description
C16 Ceramide (d18:1/16:0) is a synthetic ceramide containing sphingosine with palmitic acid. It is synthesized from ceramide synthase 6 (CerS6). C16 Ceramide-d7 (d18:1-d7/16:0) is a deuterated derivative of ceramide d18:1/16:0.
Application
C16 Ceramide-d7 (d18:1-d7/16:0), has been used as a standard to measure the amount of C16 ceramide in skeletal muscle by liquid chromatography–mass spectrometry (LC-MS).
Biochem/physiol Actions
C16 Ceramide plays a vital role in apoptotic signaling. Examining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma facilitates the prognosis of fatal outcome of coronary artery disease. A newly described and validated liquid chromatography-tandem mass spectrometry methodology uses C16 Ceramide (d18:1/16:0) in a stable isotope form for their clinical-scaled measurement.
Packaging
5 mL Amber Glass Screw Cap Vial (860676P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Anna Zalewska et al.
Biomolecules, 9(12) (2019-12-19)
This is the first study to investigate the relationship between ceramides, the mitochondrial respiratory system, oxidative stress, inflammation, and apoptosis in the submandibular gland mitochondria of mice with insulin resistance (IR). The experiment was conducted on 20 male C57BL/6 mice
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 860676P-1MG | 04061835191826 |