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Merck

791649C

Avanti

18:1-d9 SM

Avanti Research - A Croda Brand

동의어(들):

N-oleoyl(d9)-D-erythro-sphingosylphosphorylcholine

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C41H72 D9N2O6P
CAS 번호:
Molecular Weight:
738.12
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141825
Assay:
>99% (TLC)
Form:
liquid
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assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (791649C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

1 mg/mL (791649C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

18:1-d9 SM (N-oleoyl(d9)-D-erythro-sphingosylphosphorylcholine) is a deuterated derivative of 18:1-SM (N-oleoyl-D-erythro-sphingosylphosphorylcholine). 18:1- SM is a sphingomyelin which is present in aqueous humor. 18:1-SM or oleoyl-sphingomyelin, comprises quaternary ammonium group. 18:1-SM or oleoyl-sphingomyelin due to its miscible property is incapable of sequestering with cholesterol-rich domains.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH LIPIDOMIX Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

18:1-d9 SM (N-oleoyl(d9)-D-erythro-sphingosylphosphorylcholine) has been used as an extraction buffer component for lipid isolation from raft and non-raft fractions of synaptic vesicles (SV) from rat brain. It may be used as an internal standard to spike serum lipid extracts for liquid chromatography-mass spectrometry (LC/MS) analysis and ultra-high-performance supercritical fluid chromatography with quadrupole-time-of-flight mass spectrometry (UHPSFC/QTOF-MS) for signal normalization and quantification of pulmonary artery lipids form porcine.

Packaging

5 mL Clear Glass Sealed Ampule (791649C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

저장 등급

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문



Ayman J Aljohani et al.
Molecular vision, 19, 1966-1984 (2013-09-27)
To determine the differential profiles of sphingomyelin, sphingoid base, sphingoid base-1-phosphate and ceramide lipid species and their quantitative differences between control and glaucomatous aqueous humor (AQH) derived from human donors. AQH from control and primary open-angle glaucoma donors was collected
John Williams et al.
Bioanalysis, 12(3), 143-158 (2020-02-14)
Aim: Very long chain fatty acids (VLCFAs) have been identified as biomarkers for several peroxisomal disorders necessitating the need for reliable biomarker assays in particular C20, C22, C24, C26 in cerebrospinal fluid (CSF). Until now no absolute quantitation assay for
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid



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SKUGTIN
791649C-1MG04061837665981