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Merck

860679P

Avanti

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))

Avanti Research - A Croda Brand

동의어(들):

N-nervonoyl-D-erythro-sphingosine (d7)

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C42H74D7NO3
CAS 번호:
Molecular Weight:
655.14
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
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제품 이름

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)), Avanti Research - A Croda Brand 860679P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860679P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860679P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]

InChI key

VJSBNBBOSZJDKB-PVDQZAGSSA-N

General description

C24:1 Ceramide (d18:1/24:1) is a synthetic ceramide derived from sphingosine with nervonic acid (a monounsaturated analog of lignoceric acid (24:0)). C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) is a deuterated derivative of C24:1 Ceramide (d18:1/24:1).

Application

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24:1 ceramide in skeletal muscle. It has also been used as a standard to measure C40-C44 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery.

Biochem/physiol Actions

Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma aids the prognosis of fatal outcome of coronary artery disease. C24:1 Ceramide (d18:1/24:1) in a stable isotope form is suitable for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860679P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


저장 등급

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available



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문서 라이브러리 방문



Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the



국제 무역 품목 번호

SKUGTIN
860679P-1MG04061835191840