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Merck

ITGAV

integrin, alpha V

동의어:
CD51, MSK8, VNRA, VTNR
:
UniProtKB ID:
Clone ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

제품 번호
설명
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-ITGAV antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free), clone 272-17E6, from mouse,
종별 반응성
human
응용분야
activity assay
flow cytometry

immunoprecipitation (IP)
Anti-Integrin αV Antibody, clone P3G8, clone P3G8, Chemicon®, from mouse,
종별 반응성
human
응용분야
ELISA
flow cytometry

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ3 Antibody, clone LM609, biotin conjugated, clone LM609, Chemicon®, from mouse,
종별 반응성
avian, bovine, canine, chicken, human, monkey, pig, rabbit
응용분야
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51, clone SNAKA51, from mouse, purified by using protein G,
종별 반응성
human
응용분야
activity assay
immunocytochemistry

western blot

Proteins

제품 번호
설명
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
human
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Itgav,
mouse
MISSION® esiRNA, targeting human ITGAV,
human