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Y0001482

Hydrocortisone 21-acetate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

21-acétate de 11β,17α,21-trihydroxy-4-pregnène-3,20-dione, 21-acétate de 17-hydroxycorticostérone, 21-acétate de 4-pregnène-11β,17α,21-triol-3,20-dione, Acétate de 17-α-hydroxycorticostérone

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A propos de cet article

Formule empirique (notation de Hill) :
C23H32O6
Numéro CAS:
50-03-3
Poids moléculaire :
404.50
Beilstein/REAXYS Number:
2066841
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329831449
MDL number:
MFCD00037714
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grade

pharmaceutical primary standard

API family

hydrocortisone

manufacturer/tradename

EDQM

mp

223 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChI key

ALEXXDVDDISNDU-JZYPGELDSA-N

Gene Information

human ... NR3C1(2908)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrocortisone acetate for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Repr. 1B - STOT RE 2

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Adamo Fini et al.
AAPS PharmSciTech, 9(3), 762-768 (2008-06-20)
The purpose of this research was the preparation of four formulations containing hydrocortisone acetate (HCA) for topical application, including two aqueous systems (hydrophilic microemulsion and aqueous gel) and two systems with dominant hydrophobicity (hydrophobic microemulsion and ointment). The formulations were
Janyce A Sugui et al.
Journal of clinical microbiology, 52(10), 3707-3721 (2014-08-08)
Aspergillus section Fumigati contains 12 clinically relevant species. Among these Aspergillus species, A. fumigatus is the most frequent agent of invasive aspergillosis, followed by A. lentulus and A. viridinutans. Genealogical concordance and mating experiments were performed to examine the relationship
Timothy Kassis et al.
PLoS neglected tropical diseases, 8(11), e3305-e3305 (2014-11-21)
Lymphatic Filariasis, a Neglected Tropical Disease, is caused by thread-like parasitic worms, including B. malayi, which migrate to the human lymphatic system following transmission. The parasites reside in collecting lymphatic vessels and lymph nodes for years, often resulting in lymphedema
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Numéro d'article de commerce international

RéférenceGTIN
Y000148204061833808030