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1317302

USP

Hydrocortisone butyrate

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Hydrocortisone 17-butyrate, 11β,17,21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate, Cortisol 17-butyrate

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A propos de cet article

Formule empirique (notation de Hill) :
C25H36O6
Numéro CAS:
Poids moléculaire :
432.55
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

hydrocortisone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(OC(=O)CCC)C(=O)CO

InChI

1S/C25H36O6/c1-4-5-21(30)31-25(20(29)14-26)11-9-18-17-7-6-15-12-16(27)8-10-23(15,2)22(17)19(28)13-24(18,25)3/h12,17-19,22,26,28H,4-11,13-14H2,1-3H3/t17-,18-,19-,22+,23-,24-,25-/m0/s1

InChI key

BMCQMVFGOVHVNG-TUFAYURCSA-N

Gene Information

human ... NR3C1(2908)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrocortisone butyrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Hydrocortisone Butyrate Cream

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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G E Piérard
Revue medicale de Liege, 61(2), 128-130 (2006-03-29)
Since half a century, dermocorticoids represent worthy compounds in dermatological therapy. About thirty years ago, hydrocortisone 17-butyrate was introduced on the Belgian market. This compound combines good efficiency and reduced risk of side effects. Its topical formulations have been enriched
Xiaoyan Yang et al.
AAPS PharmSciTech, 15(3), 569-587 (2014-02-08)
The aim of this investigation was to develop hydrocortisone butyrate (HB)-loaded poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NP) with ideal encapsulation efficiency (EE), particle size, and drug loading (DL) under emulsion solvent evaporation technique utilizing various experimental statistical design modules. Experimental designs



Numéro d'article de commerce international

RéférenceGTIN
1317302-200MG04061833860182