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Merck

80457

Trifluoroacetic acid

eluent additive for LC-MS, LiChropur, ≥99.0% (GC)

동의어(들):

TFA

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CF3COOH
CAS 번호:
Molecular Weight:
114.02
EC Number:
200-929-3
UNSPSC Code:
41116105
NACRES:
NB.21
Beilstein/REAXYS Number:
742035
MDL number:
Assay:
≥99.0% (GC)
Form:
liquid
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vapor density

3.9 (vs air)

Quality Level

vapor pressure

97.5 mmHg ( 20 °C)

product line

LiChropur

assay

≥99.0% (GC)

form

liquid

technique(s)

LC/MS: suitable

impurities

≤0.05% water, ≤50 mg/kg total sulfur (as SO4)

refractive index

n20/D 1.3 (lit.)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

solubility

water: soluble 10,000 g/L

density

1.489 g/mL at 20 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfite (SO32-): ≤10 mg/kg

cation traces

Ag: ≤0.05 mg/kg, Al: ≤0.1 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.5 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.1 mg/kg, Co: ≤0.05 mg/kg, Cr: ≤0.1 mg/kg, Cu: ≤0.05 mg/kg, Fe: ≤1.0 mg/kg, K: ≤1.0 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤1.0 mg/kg, Mn: ≤0.1 mg/kg, Mo: ≤0.05 mg/kg, NH4+: ≤10 mg/kg, Na: ≤1.0 mg/kg, Ni: ≤0.1 mg/kg, Pb: ≤0.05 mg/kg, Sr: ≤0.05 mg/kg, Tl: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg

SMILES string

OC(C(F)(F)F)=O

UV absorption

λ: 260 nm Amax: ≤0.9, λ: 270 nm Amax: ≤0.1, λ: 280 nm Amax: ≤0.08, λ: 290 nm Amax: ≤0.07, λ: 300 nm Amax: ≤0.06, λ: 320 nm Amax: ≤0.05

suitability

passes test for LC-MS

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

General description

Trifluoroacetic acid is commonly used as a mobile phase additive in liquid chromatography-mass spectrometry (LC-MS).
Features:
  • Extensive QC testing ensures the highest specifications.        
  • Optimized to improve ionization and resolution.        
  • Extremely low levels of inorganic and organic impurities.       
  • Manufactured specifically for accurate and fast LC-MS.

Application

Trifluoroacetic acid may be used as a mobile phase additive for the analysis of basic compounds in biological samples using hydrophilic interaction liquid chromatography-electrospray ionization coupled to tandem mass spectrometry (HILIC–ESI/MS/MS) and reversed-phase liquid chromatography coupled to tandem mass spectrometry (RP-LC-MS/MS).

Packaging

Clear borosilicate glass, high hydrolytic resistance (Type I)

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

저장 등급

8B - Non-combustible corrosive hazardous materials

wgk

WGK 2



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시험 성적서(COA)

Lot/Batch Number

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모든 프로토콜 보기

문서

The article describes the use of difluoroacetic acid (DFA) as an effective alternative to acid modifiers, formic acid (FA) and trifluoroacetic acid (TFA) in the LC-UV/MS analysis of proteins.

Compare columns in resolving medium-sized antibody fragments after digestion with DTT or IdeS using Reversed-Phase Chromatography for analysis.

Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.

모든 기사 보기

관련 콘텐츠

ZipTip® micro-SPE pipette tips are used as a single-step desalting, concentration, and purification tool for complex samples before mass spec analyses.


Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography?electrospray tandem mass spectrometric (HILIC?ESI/MS/MS) bioanalysis of basic compounds
Shou ZW and Naidong W
Journal of Chromatography. B, Biomedical Sciences and Applications, 825(2), 186-192 (2005)



국제 무역 품목 번호

SKUGTIN
80457-10ML04065269358688
80457-10X1ML04065269358695
80457-1ML-KC04065269350422
80457-50ML-B04065269350439