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1.37002

Citric acid

Name: Citric acid
Brand: MM

anhydrous powder, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

동의어(들):

2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

HOC(COOH)(CH₂COOH)₂

CAS 번호:

77-92-9

Molecular Weight:

192.12

EC Index Number:

201-069-1

UNSPSC Code:

12352106

Beilstein/REAXYS Number:

782061

MDL number:

MFCD00011669

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도움 문의

속성

Quality Level

500

agency

BP, ChP, JP, Ph. Eur., USP

vapor pressure

<0.1 hPa ( 20 °C)

product line

EMPROVE^® EXPERT

assay

99.5-100.5% substance (anhydrous) basis (alkalimetric)

form

fine powder, solid

feature

RNase and DNase free

expl. lim.

8 %, 65 °F

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

impurities

endotoxins, low

pH

1.7 (20 °C, 100 g/L in H₂O)

pKa

(1) 3.13, (2) 4.76, (3) 6.4

bp

200 °C/1013 hPa (decomposition)

mp

153-159 °C (lit.)

solubility

water: 1330 g/L at 20 °C

density

1.665 g/cm³ at 18 °C

cation traces

Al: ≤0.2 ppm, Fe: ≤3 ppm, Pb: ≤2 ppm, heavy metals (as Pb): ≤10 ppm

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

15-25°C

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

설명

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Citric acid anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Citric acid anhydrous Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under

pictograms

GHS07

signalword

Warning

hcodes

H319,H335

pcodes

P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c