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Merck

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1.37003

Citric acid monohydrate

crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

동의어(들):

2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
HOC(COOH)(CH2COOH)2 · H2O
CAS 번호:
5949-29-1
Molecular Weight:
210.14
EC Index Number:
201-069-1
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
4018641
MDL number:
MFCD00149972
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도움 문의

Quality Level

500

agency

BP, ChP, JP, Ph. Eur., USP

vapor pressure

<1 Pa ( 25 °C)

description

cryst. EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP

product line

EMPROVE® EXPERT

form

crystalline, solid

feature

RNase and DNase free

impurities

endotoxins, low

pH

1.85 (25 °C, 50 g/L in H2O)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

135-152 °C

transition temp

flash point 173.9 °C

solubility

880 g/L

density

1.54 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

15-25°C

SMILES string

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

InChI key

YASYEJJMZJALEJ-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Citric acid anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Citric acid anhydrous Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

345.0 °F - closed cup

flash_point_c

173.9 °C - closed cup

시험 성적서(COA)

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관련 콘텐츠

Formulation

Learn more on mAb subcutaneous or intravenous formulation, and the relevant associated products, including excipients.

국제 무역 품목 번호

SKUGTIN
137003901204027269077426
137003000104027269365233
137003100004027269364946
137003500004027269061432
137003902904027269061968