QBD10194
NHS-S-S-dPEG®4-biotin (cleavable)
동의어(들):
2,5-Dioxo-1-pyrrolidinyl 29-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-9,25-dioxo-12,15,18,21-tetraoxa-4,5-dithia-8,24-diazanonacosanoate, Polyethylene glycol
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C30H49N5O11S3
CAS 번호:
Molecular Weight:
751.93
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22
assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: Biotinylations, reagent type: cross-linking reagent
functional group
disulfide
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(NCCSSCCC(ON1C(CCC1=O)=O)=O)CCOCCOCCOCCOCCNC(CCCCC2C3NC(NC3CS2)=O)=O
InChI
1S/C30H49N5O11S3/c36-24(4-2-1-3-23-29-22(21-47-23)33-30(41)34-29)31-9-12-43-14-16-45-18-17-44-15-13-42-11-7-25(37)32-10-20-49-48-19-8-28(40)46-35-26(38)5-6-27(35)39/h22-23,29H,1-21H2,(H,31,36)(H,32,37)(H2,33,34,41)
InChI key
QEVJWOMRMWJABZ-UHFFFAOYSA-N
Features and Benefits
NHS-S-S-dPEG®4-biotin is used extensively to label molecules that contain a free amine with biotin. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin. NHS-S-S-dPEG®4-biotin contains a disulfide group in the linear chain, allowing the biotin to be cleaved reductively from the labeled molecule.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| QBD10194-500MG | 04061832876795 |
| QBD10194-50MG | 04061832876801 |