913669
Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid
동의어(들):
N-(2-((2-Aminoethyl)disulfaneyl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 2,2,2-trifluoroacetate, Biotin-SS-NH2 TFA, Biotin-cystamine TFA, Cleavable biotin linker
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C16H27F3N4O4S3
CAS 번호:
Molecular Weight:
492.60
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22
form
powder
Quality Level
storage temp.
−20°C
SMILES string
OC(C(F)(F)F)=O.NCCSSCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O
InChI
1S/C14H26N4O2S3.C2HF3O2/c15-5-7-22-23-8-6-16-12(19)4-2-1-3-11-13-10(9-21-11)17-14(20)18-13;3-2(4,5)1(6)7/h10-11,13H,1-9,15H2,(H,16,19)(H2,17,18,20);(H,6,7)/t10-,11-,13-;/m0./s1
InChI key
IEBCHCOZFAGWJW-SQRKDXEHSA-N
Application
Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid (Biotin-SS-NH2 TFA) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.
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저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Toshiyuki Kan et al.
Organic letters, 9(11), 2055-2058 (2007-05-08)
Convenient synthesis of a variety of photoaffinity probes was accomplished by utilizing our Ns strategy and novel resin. The synthetic probes were evaluated via the labeling ability with the preseniline 1 C-terminal fragments, which was identified as a therapeutic target
Claudio Gnaccarini et al.
Bioorganic & medicinal chemistry, 17(17), 6354-6359 (2009-08-08)
Herein, we report the development of a direct discontinuous fluorometric transamidation assay for determining tissue transglutaminase (TG2) activity. In the assay reaction, TG2 catalyzes the formation of a biotin-fluorophore conjugate, using a fluorescent, high affinity gamma-glutamyl donor substrate and a
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 913669-50MG | 04061842082797 |