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Merck

902667

Propargyl-PEG6-acid

동의어(들):

4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, Propargyl-PEG6-CH2CO2H

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C16H28O8
CAS 번호:
Molecular Weight:
348.39
UNSPSC Code:
12352106
NACRES:
NA.22
MDL number:
기술 서비스
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assay

≥95%

form

liquid

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent

refractive index

n/D 1.469

functional group

alkyne, carboxylic acid

storage temp.

−20°C

SMILES string

OC(CCOCCOCCOCCOCCOCCOCC#C)=O

InChI

1S/C16H28O8/c1-2-4-19-6-8-21-10-12-23-14-15-24-13-11-22-9-7-20-5-3-16(17)18/h1H,3-15H2,(H,17,18)

InChI key

XRSJYQQOJNYUDV-UHFFFAOYSA-N

Application

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophilic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license


저장 등급

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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시험 성적서(COA)

Lot/Batch Number

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국제 무역 품목 번호

SKUGTIN
902667-1G04061838694379
902667-250MG04061838694386