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850150P

Avanti

18:1 PI(3)P

Avanti Research™ - A Croda Brand

Synonyme(s) :

PIP[3′](18:1/18:1)

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A propos de cet article

Formule empirique (notation de Hill) :
C45H90N2O16P2
Numéro CAS:
1246303-09-2
Poids moléculaire :
977.15
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′-phosphate) (ammonium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850150P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850150P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C45H84O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(46)57-35-37(59-39(47)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)36-58-63(55,56)61-45-42(50)40(48)41(49)44(43(45)51)60-62(52,53)54;;/h17-20,37,40-45,48-51H,3-16,21-36H2,1-2H3,(H,55,5

InChI key

BYXVELJOJLXSIL-ADVUQDOQSA-N

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol phosphate is present in the plasma membrane.

Application

18:1 PIP has been used in liposome preparation. It may also be used to generate small unilamellar vesicles for liposome flotation assays.

Biochem/physiol Actions

Phosphatidylinositol phosphate helps to promote the plasma membrane H+-ATPase of Saccharomyces cerevisiae. Phosphatidylinositol 3-phosphate (PtdIns3P) is very essential for the biogenesis of autophagosomes and their precursors.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850150P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850150P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Classe de stockage

11 - Combustible Solids

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Consulter la Bibliothèque de documents

Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion
Dolat L and Spiliotis ET
The Journal of Cell Biology, 214(5), 517-527 (2016)
Mariko Yokogawa et al.
The Journal of biological chemistry, 287(42), 34936-34945 (2012-08-24)
Phosphoinositides (PIs) are crucial lipid components of membranes and are involved in a number of cellular processes through interactions with their effector proteins. Recently, we have established a lipid-protein nanoscale bilayer (nanodisc) containing PIs, hereafter referred to as PI-nanodisc and
Richard J Chi et al.
The Journal of cell biology, 204(5), 793-806 (2014-02-26)
Retromer is an endosomal sorting device that orchestrates capture and packaging of cargo into transport carriers coated with sorting nexin BAR domain proteins (SNX-BARs). We report that fission of retromer SNX-BAR-coated tubules from yeast endosomes is promoted by Vps1, a
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Numéro d'article de commerce international

RéférenceGTIN
850150P-500UG04061835229543
850150P-100UG04061835229536