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A propos de cet article
Formule empirique (notation de Hill) :
C40H80NO8P
Numéro CAS:
Poids moléculaire :
734.04
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Service technique
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1,2-dipalmitoyl-sn-glycero-3-phosphocholine
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (850355P-1g), pkg of 1 × 200 mg (850355P-200mg), pkg of 1 × 25 mg (850355P-25mg), pkg of 1 × 500 mg (850355P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3
InChI key
KILNVBDSWZSGLL-UHFFFAOYSA-N
General description
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is synthesized from unsaturated phosphatidylcholine (PC) by direct de novo synthesis via α1,2-dipalmitoyl diacylglycerol intermediate. The enzyme cholinephosphotransferase catalyzes the conversion of 1,2-dipalmitoyl diacylglycerol to DPPC. Synthesis of DPPC also occurs via remodeling pathway involving deacylation of unsaturated PC.
Application
16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.
Biochem/physiol Actions
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is a surfactant and reduces surface tension. It is used in combination with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) for lipid bilayer generation. DPPC alone and in combination with other phospholipid is effective in drug encapsulation and delivery.
Packaging
20 mL Clear Glass Screw Cap Vial (850355P-1g)
20 mL Clear Glass Screw Cap Vial (850355P-500mg)
5 mL Amber Glass Screw Cap Vial (850355P-200mg)
5 mL Amber Glass Screw Cap Vial (850355P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells
Chen X, et al.
Proceedings of the National Academy of Sciences of the USA, 103(31), 11724-11729 (2006)
Norbert Kučerka et al.
Langmuir : the ACS journal of surfaces and colloids, 33(12), 3134-3141 (2017-03-10)
Interactions of calcium (Ca2+) and zinc (Zn2+) cations with biomimetic membranes made of dipalmitoylphosphatidylcholine (DPPC) were studied by small angle neutron diffraction (SAND). Experiments show that the structure of these lipid bilayers is differentially affected by the two divalent cations.
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 850355P-1G | 04061835230341 |
| 850355P-200MG | 04061835230358 |
| 850355P-25MG | 04061835230365 |
| 850355P-500MG | 04061835230372 |