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850151P

Avanti

18:1 PI(4)P

Avanti Research™ - A Croda Brand

Synonyme(s) :

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)

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A propos de cet article

Formule empirique (notation de Hill) :
C45H90N2O16P2
Numéro CAS:
1803104-55-3
Poids moléculaire :
977.15
UNSPSC Code:
51191904
NACRES:
NA.25
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Nom du produit

18:1 PI(4)P, Avanti Research™ - A Croda Brand 850151P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850151P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850151P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850151P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C45H84O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(46)57-35-37(59-39(47)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)36-58-63(55,56)61-45-42(50)40(48)44(41(49)43(45)51)60-62(52,53)54;;/h17-20,37,40-45,48-51H,3-16,21-36H2,1-2H3,(H,55,5

InChI key

XDKQBHORSIMQSB-QVUMANCCSA-N

General description

18:1 PI(5)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) is an ammonium salt of modified lipid which bears a double at the 9th carbon of dioleoyl group. Phosphatidylinositol 4-phosphate (PI-4-P) is an abundant phosphoinositide species present in the plasma membrane.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

18:1 PI(5)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)) has been used in protein−lipid overlay assay. It may be used in small unilamellar vesicles for liposome flotation assays. It may also be used in different lipid binding specificity studies.

Biochem/physiol Actions

Phosphatidylinositol 4-phosphate (PI-4-P) is an important factor, that is required for membrane traffic, polarized growth and cytoskeleton organization.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850151P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850151P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

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Consulter la Bibliothèque de documents

Vikram Ghugtyal et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(28), 8644-8649 (2015-07-01)
The phospholipid phosphatidylinositol-4-phosphate [PI(4)P], generated at the Golgi and plasma membrane, has been implicated in many processes, including membrane traffic, yet its role in cell morphology changes, such as the budding to filamentous growth transition, is unknown. We show that
Chao-Yuan Yu et al.
Plant physiology, 183(1), 221-235 (2020-03-25)
Phosphoinositides function as lipid signals in plant development and stress tolerance by binding with partner proteins. We previously reported that Arabidopsis (Arabidopsis thaliana) phosphoinositide-specific phospholipase C2 functions in the endoplasmic reticulum (ER) stress response. However, the underlying molecular mechanisms of
Mark R Lundquist et al.
Molecular cell, 70(3), 531-544 (2018-05-05)
While the majority of phosphatidylinositol-4, 5-bisphosphate (PI-4, 5-P2) in mammalian cells is generated by the conversion of phosphatidylinositol-4-phosphate (PI-4-P) to PI-4, 5-P2, a small fraction can be made by phosphorylating phosphatidylinositol-5-phosphate (PI-5-P). The physiological relevance of this second pathway is
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Numéro d'article de commerce international

RéférenceGTIN
850151P-100UG04061835229550
850151P-500UG04061835229567