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KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2

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NACRES:
NA.21
UNSPSC Code:
12161600
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product line

KitAlysis

reaction suitability

reagent type: catalyst
core: palladium
reaction type: Miyaura Borylation Reaction

functional group

phosphine

General description

The KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit enables chemists to quickly and efficiently screen reaction conditions for Pd catalyzed Miyaura borylation reactions. Quick identification of optimal conditions allows faster scale-up of the desired synthetic transformation. All required chemicals come pre-weighed for ease of use. A step-by-step user guide and experimental excel sheets are available for download to facilitate the process.

Application

Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.
Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit
Downloadable Experiment excel sheets

Each kit contains 2 customizable screening sets that include the following components:

  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 4 x 4 mL reaction vials with pre-weighed KOAc
  • Bis(pinacolato)diboron (473294), tetrahydroxydiboron (754242), and pinacol (221171)
  • 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA.
  • 1 NEW KitAlysis 24-Well Reaction Block Replacement Film.
  • 4 stir bars for substrate stock solution vials.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC


Composants de kit également disponibles séparément

Réf. du produit
Description
FDS & Tarif

  • P(Cy3) Pd G3, 97%
    FDS

  • Potassium acetate, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.0%
    FDS

  • XPhos Pd G4, 95%
    FDS

  • SPhos Pd G4
    FDS

  • RuPhos Pd G4
    FDS

  • DTBPF-Pd-G3
    FDS

  • cataCXium A Pd G4
    FDS

Afficher tout (21)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT RE 2 Oral - STOT SE 1 - STOT SE 3

target_organs

Central nervous system, Eyes,Central nervous system, Kidney, Respiratory system

supp_hazards

Classe de stockage

3 - Flammable liquids

flash_point_f

1.4 °F

flash_point_c

-17 °C

wgk

WGK 3



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Protocoles

Catalyst screening kits, KitAlysis™, and TLC-MS analysis enable high-throughput synthesis and analysis for efficient reactions.

Articles

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Contenu apparenté

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

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RéférenceGTIN
KITALYSIS-BOR-2PK04061833450949