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KitAlysis High-Throughput Suzuki-Miyaura Cross-Coupling Reaction Screening Kit - Pack of 4

Synonyme(s) :

Suzuki-Miyaura Cross-Coupling

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NACRES:
NA.22
UNSPSC Code:
12161600
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product line

KitAlysis

reaction suitability

reaction type: Cross Couplings, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
core: palladium

functional group

phosphine

Application

Screening kit for Suzuki-Miyaura cross-coupling reaction. Step-by-step user guide and a downloadable experimental excel sheets are provided in the below hyperlink.
Step-by-Step Guide for Suzuki-Miyaura Cross-Coupling Reaction Screening Kit
Downloadable experimental excel sheet

Each kit contains 4 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 1 (2 mL) ampule each of Toluene, THF, n-Butanol, DMAc, and aq. 1.5 M K3PO4.
  • 4 NEW KitAlysis 24-Well Reaction Block Replacement Films.
  • 4 substrate reaction vials with stir bars.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC


Composants de kit seuls

Réf. du produit
Description

  • SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules 1 EA

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS & Tarif

  • Pd-PEPPSI-IPent catalyst, ≥95% 5 µmol
    FDS

  • SPhos Pd G2 5 µmol
    FDS

  • cataCXium® A Pd G2 5 µmol
    FDS

  • XPhos Pd G3, 98%, 1:1 MTBE adduct 5 µmol
    FDS

  • P(Cy3) Pd G3, 97% 5 µmol
    FDS

  • APhos Pd G3, 97% 5 µmol
    FDS

  • Toluene, anhydrous, ZerO2®, 99.8% 8 mL
    FDS

Afficher tout (12)

signalword

Danger

target_organs

Central nervous system, Respiratory system

supp_hazards

Classe de stockage

3 - Flammable liquids

flash_point_f

1.4 °F

flash_point_c

-17 °C

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3



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Protocoles

A step-by-step protocol guide for KitAlysis Suzuki-Miyaura Cross-Coupling Reaction Screening Kit.

Articles

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Tools aid in kit setup for organic chemistry techniques, ensuring ease and success.

All of the preformed catalysts used in the kit are air and moisture stable complexes in their commercially available form.

Voir tous les articles

Contenu apparenté

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

Voir tous les contenus connexes

High-Throughput Experimentation in Catalysis and Materials Science.
Gordillo A, et al.
Ullmann's Encyclopedia of Industrial Chemistry (2014)
Scientist-Led High-Throughput Experimentation (HTE) and Its Utility in Academia and Industry.
Schmink JR, et al.
Aldrichimica Acta, 46, 71-80 (2013)
Spencer D Dreher et al.
Journal of the American Chemical Society, 130(29), 9257-9259 (2008-06-28)
Microscale parallel experimentation was used to discover three catalyst systems capable of coupling secondary organotrifluoroborates with sterically and electronically demanding aryl chlorides and bromides. The ensuing results represent the first comprehensive study of alkylboron coupling to aryl chlorides and, in



Numéro d'article de commerce international

RéférenceGTIN
KITALYSIS-SM-4PAK04061833553756