910015
17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid
≥95%
Synonym(s):
Azido-PEG5-CH2CO2H, Azido-PEG5-acid, N3-PEG5-CH2COOH
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About This Item
Empirical Formula (Hill Notation):
C12H23N3O7
CAS Number:
Molecular Weight:
321.33
UNSPSC Code:
12352106
MDL number:
Assay:
≥95%
Form:
(Liquid or Semi-solid or Paste or Solid)
assay
≥95%
form
(Liquid or Semi-solid or Paste or Solid)
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
functional group
azide, carboxylic acid
storage temp.
2-8°C
SMILES string
OC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O
Application
This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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