SRP0349
Flt3 active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
동의어(들):
CD135, FLK2, STK1, fms-related tyrosine kinase 3
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
Form:
aqueous solution
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
54.2 kDa
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
54.2 kDa
packaging
pkg of 10 μg
technique(s)
activity assay: suitable, inhibition assay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... FLT3(2322)
General description
Human Flt3 (GenBank Accession No. NM_004119), amino acids 564-end with N-terminal His-tag, MW=54.2 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Connor P Hall et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(3), 621-632 (2015-06-18)
The aim of our study is to evaluate the preclinical therapeutic activity and mechanism of action of BEZ235, a dual PI3K/mTOR inhibitor, in combination with dexamethasone in acute lymphoblastic leukemia (ALL). The cytotoxic effects of BEZ235 and dexamethasone as single
Mark Levis et al.
Blood, 106(2), 673-680 (2005-03-31)
Internal tandem duplication mutations of the FLT3 gene (FLT3/ITD mutations) are the most frequent molecular abnormality in acute myeloid leukemia (AML) and are associated with a poor overall survival. While the normal FLT3 receptor is expressed in early hematopoietic progenitor
Shinichiro Takahashi et al.
Leukemia research, 29(8), 893-899 (2005-06-28)
Activating mutations or over-expression of the Flt3 is prevalent in acute myeloblastic leukemia (AML), associated with activation of Ras/MAP kinase and other signaling pathways. In this study, we addressed the role of Flt3 in the activation of nuclear factor-kappa B
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| SRP0349-10UG | 04061837195907 |