SML1504
Tegaserod maleate
≥98% (HPLC)
동의어(들):
2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentyl-hydrazinecarboximidamide maleate
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C16H23N5O · C4H4O4
CAS 번호:
Molecular Weight:
417.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
N=C(NCCCCC)N/N=C/C1=CNC2=C1C=C(OC)C=C2.OC(/C=C\C(O)=O)=O
InChI
1S/C16H23N5O.C4H4O4/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15;5-3(6)1-2-4(7)8/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21);1-2H,(H,5,6)(H,7,8)/b20-11+;2-1-
InChI key
CPDDZSSEAVLMRY-FEQFWAPWSA-N
Gene Information
human ... HTR4(3360)
Application
Tegaserod maleate has been used to study its cytotoxic effects on human astrocytes and to study its effects as an anti-glioblastoma agent.
Biochem/physiol Actions
Tegaserod is a potent full agonist at serotonin 5-HT4 receptors with an EC50 of 7 nM.
Tegaserod is a serotonin 5-HT4 agonist.
It stimulates neurotransmitter release from enteric nerves and regularizes gastrointestinal function. Tegaserod has been used to treat irritable bowel syndrome associated with constipation and chronic constipation.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Screening of clinically-applicable drugs in patient-derived glioblastoma stem-like cells identifies amiodarone, clofazimine and triptolide as potential anti-glioma agents
Sigrid S
Combinatorial Chemistry: From Theory to Application (2015)
Corrado Blandizzi and Carmelo Scarpignato
Side Effects of Drugs Annual: A world-wide yearly survey of new data and trends in adverse drug reactions., 33, 741-767 (2011)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| SML1504-50MG | 04061832077628 |
| SML1504-10MG | 04061832077611 |