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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C23H31NO7
CAS 번호:
Molecular Weight:
433.49
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
제품 이름
Mycophenolate mofetil, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥15 mg/mL
storage temp.
room temp
SMILES string
COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OCCN3CCOCC3
InChI
1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+
InChI key
RTGDFNSFWBGLEC-SYZQJQIISA-N
Gene Information
human ... IMPDH1(3614), IMPDH2(3615)
Application
Mycophenolate mofetil has been used to treat wild-type embryos for inhibiting nucleotide synthesis.
Biochem/physiol Actions
Mycophenolate mofetil is a prodrug of mycophenolic acid (Cat. # M5255) that is cleaved by nonspecific esterases in vivo to produce the parent compound. Mycophenolic acid blocks inosine monophosphate dehydrogenase and is a potent immunosuppresive agent.
Mycophenolate mofetil is a prodrug of mycophenolic acid and potent immunosuppresive agent.
Mycophenolate mofetil functions as a rate-limiting enzyme in de novo synthesis of guanosine nucleotides.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Mycophenolate mofetil and its mechanisms of action
Allison AC and Eugui EM
Immunopharmacology, 47(2-3), 85-118 (2000)
Wuhong Pei et al.
Scientific reports, 6, 29946-29946 (2016-07-19)
Phosphoribosyl pyrophosphate synthetase-1 (PRPS1) is a key enzyme in nucleotide biosynthesis, and mutations in PRPS1 are found in several human diseases including nonsyndromic sensorineural deafness, Charcot-Marie-Tooth disease-5, and Arts Syndrome. We utilized zebrafish as a model to confirm that mutations
Eduardo F Mysler et al.
Arthritis and rheumatism, 65(9), 2368-2379 (2013-06-07)
To investigate the efficacy and safety of ocrelizumab in patients with class III/IV lupus nephritis (LN). Patients were randomized 1:1:1 to receive placebo, 400 mg ocrelizumab, or 1,000 mg ocrelizumab given as an intravenous infusion on days 1 and 15
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| SML0284-10MG | 04061832633169 |
| SML0284-50MG | 04061832633176 |


