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Merck

SAB5702859

Anti-KRAS+HRAS+NRAS Antibody

rabbit monoclonal, 6S6F3

동의어(들):

ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.46
Clone:
6S6F3, monoclonal
Technique(s):
immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000
Application:
IF, WB
Citations:
-
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제품 이름

Anti-KRAS+HRAS+NRAS Antibody, clone 6S6F3, Rabbit Monoclonal,

biological source

rabbit

Quality Level

material

colorless

clone

6S6F3, monoclonal

form

liquid

mol wt

20 kDa

species reactivity

human, rat

concentration

0.30 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NRAS(4893)

General description

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NRAS (P01111).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC


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SKUGTIN
SAB5702859-100UL04065270689382