Anti-CRHR2 antibody produced in rabbit

Anti-CRHR2 antibody detects endogenous levels of total CRHR2 protein.

The CRHR2 (corticotropin releasing hormone receptor 2) gene is a member of G protein coupled receptors (GPCRs) family. It is located on human chromosome 7p21-p15. It has 12 exons and approximately 50,000 base pairs (Kbp). It has 3 isoforms, such as CRHR2α β and γ out of which, CRHR2γ is mostly expressed in the brain and CRHR2α 2β are expressed in the brain and smooth muscle.

The antiserum was produced against synthesized peptide derived from human CRHR2.

Immunogen Range: 71-120

Anti-CRHR2 antibody has been used in immunoprecipitation and western blotting .{6,7}

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

CRHR2 (corticotropin releasing hormone receptor 2) is involved in the relaxation of smooth muscle response and may affect the response of acute airway bronchodilator to short acting β2 agonist treatment of asthma. Signaling pathways of CRHR2 modulate the hypothalamic-pituitary-adrenocortical axis.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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