Anti-Histone H3.1 Antibody

Anti-Histone H3 Antibody detects endogenous levels of total Histone H3 protein.

Mammals contain three main classes of histone H3 variants: the replicative histones (H3.1 and H3.2), the replacement histone (H3.3) and the centromeric histone (Cenp-A). Histone H3 is located on human chromosome 6p22.

The antiserum was produced against synthesized peptide derived from human Histone H3.

Immunogen Range: 1-50

Anti-Histone H3, N-Terminal antibody has been used in western blotting and enzyme-linked immunosorbent assay (ELISA).

Histone proteins are basic building blocks of chromatin. Histone H3 K27M mutations in adult cerebellar high-grade gliomas. It controls protein-protein interactions to induce binding of trans-acting factors that “drive” chromatin condensation.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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