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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C14H21N3O2S · C4H6O4
CAS 번호:
Molecular Weight:
413.49
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
제품 이름
Sumatriptan succinate, ≥98% (HPLC), solid
Quality Level
assay
≥98% (HPLC)
form
solid
color
white to beige
solubility
H2O: >20 mg/mL
originator
GlaxoSmithKline
SMILES string
OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI
1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
InChI key
PORMUFZNYQJOEI-UHFFFAOYSA-N
Gene Information
human ... HTR1B(3351), HTR1D(3352)
Biochem/physiol Actions
Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.
Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT1 receptor agonist can be used to treat migraine.
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Repr. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Mucoadhesive bilayered patches for administration of sumatriptan succinate
Shidhaye SS, et al.
Aaps Pharmscitech, 9(3), 909-916 (2008)
Treatment of acute migraine with subcutaneous sumatriptan
Cady RK, et al.
JAMA : The Journal of the American Medical Association, 265(21), 2831-2835 (1991)
Tse-Ming Chou et al.
The journal of headache and pain, 23(1), 157-157 (2022-12-13)
To investigate specific brain regions and neural circuits that are responsible for migraine chronification. We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose of nitroglycerin (0.1 mg/kg for 9 days) and validated the model with cephalic and
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| S1198-10MG | 04061836908928 |
| S1198-50MG | 04061836908959 |
