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Merck

S1198

Sumatriptan succinate

≥98% (HPLC), solid, 5-HT₁ receptor agonist

동의어(들):

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C14H21N3O2S · C4H6O4
CAS 번호:
Molecular Weight:
413.49
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
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제품 이름

Sumatriptan succinate, ≥98% (HPLC), solid

Quality Level

assay

≥98% (HPLC)

form

solid

color

white to beige

solubility

H2O: >20 mg/mL

originator

GlaxoSmithKline

SMILES string

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

InChI key

PORMUFZNYQJOEI-UHFFFAOYSA-N

Gene Information

Biochem/physiol Actions

Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.
Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT1 receptor agonist can be used to treat migraine.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


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pictograms

Health hazard

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Repr. 2

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문



Mucoadhesive bilayered patches for administration of sumatriptan succinate
Shidhaye SS, et al.
Aaps Pharmscitech, 9(3), 909-916 (2008)
Treatment of acute migraine with subcutaneous sumatriptan
Cady RK, et al.
JAMA : The Journal of the American Medical Association, 265(21), 2831-2835 (1991)
Tse-Ming Chou et al.
The journal of headache and pain, 23(1), 157-157 (2022-12-13)
To investigate specific brain regions and neural circuits that are responsible for migraine chronification. We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose of nitroglycerin (0.1 mg/kg for 9 days) and validated the model with cephalic and



국제 무역 품목 번호

SKUGTIN
S1198-10MG04061836908928
S1198-50MG04061836908959