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Merck

S006

Ketanserin (+)-tartrate salt

≥97%, 5-HT2 serotonin receptor antagonist, solid

동의어(들):

3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt, R 41468 (+)-tartrate salt

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C22H22FN3O3 · C4H6O6
CAS 번호:
Molecular Weight:
545.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
281-062-8
MDL number:
Assay:
≥97%
Form:
solid
Quality level:
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제품 이름

Ketanserin (+)-tartrate salt, ≥97%, solid

Quality Level

assay

≥97%

form

solid

color

white

solubility

ethanol: 3 mg/mL, DMSO: 52 mg/mL (lit.)(lit.), 0.1 M HCl: 6 mg/mL (lit.)(lit.)

storage temp.

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O

InChI

1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key

KMTLTEVOQLMYRS-LREBCSMRSA-N

Gene Information

Application

Ketanserin (+)-tartrate salt has been used:
  • as a 5HT2A antagonist in Krebs-Henseleit buffer solution
  • for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior
  • to study the behavioural changes of incision pain rats

Biochem/physiol Actions

Ketanserin stimulates collagen synthesis and is involved in wound healing.
Selective 5-HT2 serotonin receptor antagonist.
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.


pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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문서 라이브러리 방문



Effects of short-term exposure to ectoparasites on fish cortisol and hematocrit levels
Triki Z, et al.
Marine biology, 163(9), 187-187 (2016)
The 5-HT2A receptor potassium-chloride cotransporter 2 signaling pathway in a rat incision pain model
Dong R, et al.
Experimental and Therapeutic Medicine, 12(6), 3583-3588 (2016)
Ketanserin in wound healing and fibrosis: investigations into its mechanism of action
Serotonin, 12(6), 451-455 (1990)



국제 무역 품목 번호

SKUGTIN
S006-10MG04061836829971
S006-250MG04061836829988
S006-500MG04061832941424
S006-50MG04061836829995