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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C22H22FN3O3 · C4H6O6
CAS 번호:
Molecular Weight:
545.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
281-062-8
MDL number:
제품 이름
Ketanserin (+)-tartrate salt, ≥97%, solid
Quality Level
assay
≥97%
form
solid
color
white
solubility
ethanol: 3 mg/mL, DMSO: 52 mg/mL (lit.)(lit.), 0.1 M HCl: 6 mg/mL (lit.)(lit.)
storage temp.
2-8°C
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O
InChI
1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
InChI key
KMTLTEVOQLMYRS-LREBCSMRSA-N
Gene Information
human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
Application
Ketanserin (+)-tartrate salt has been used:
- as a 5HT2A antagonist in Krebs-Henseleit buffer solution
- for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior
- to study the behavioural changes of incision pain rats
Biochem/physiol Actions
Ketanserin stimulates collagen synthesis and is involved in wound healing.
Selective 5-HT2 serotonin receptor antagonist.
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Effects of short-term exposure to ectoparasites on fish cortisol and hematocrit levels
Triki Z, et al.
Marine biology, 163(9), 187-187 (2016)
The 5-HT2A receptor potassium-chloride cotransporter 2 signaling pathway in a rat incision pain model
Dong R, et al.
Experimental and Therapeutic Medicine, 12(6), 3583-3588 (2016)
Ketanserin in wound healing and fibrosis: investigations into its mechanism of action
Serotonin, 12(6), 451-455 (1990)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| S006-10MG | 04061836829971 |
| S006-250MG | 04061836829988 |
| S006-500MG | 04061832941424 |
| S006-50MG | 04061836829995 |
