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Q1004

Quipazine maleate salt

Name: Quipazine maleate salt
Brand: SIGMA

serotonin/5-hydroxytryptamine-2A/C receptor agonist

동의어(들):

2-(1-Piperazinyl)quinoline maleate salt

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₃H₁₅N₃ · C₄H₄O₄

CAS 번호:

5786-68-5

Molecular Weight:

329.35

NACRES:

NA.77

PubChem Substance ID:

24278122

UNSPSC Code:

12352200

EC Number:

227-314-2

MDL number:

MFCD00133796

Quality level:

200

기술 서비스

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도움 문의

속성

제품 이름

Quipazine maleate salt,

Quality Level

200

solubility

H₂O: soluble, alcohol: soluble, dilute aqueous acid: soluble

storage temp.

2-8°C

SMILES string

OC(=O)\C=C/C(O)=O.C1CN(CCN1)c2ccc3ccccc3n2

InChI

1S/C13H15N3.C4H4O4/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16;5-3(6)1-2-4(7)8/h1-6,14H,7-10H2;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

QYJJDHZHSCTBII-BTJKTKAUSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

설명

Application

Quipazine maleate salt has been used as a serotonin receptor agonist to study its effects on mouse models with spinal cord injury. It has also been used as a serotonin receptor agonist to study its effects on the locomotion of zebrafish.

Biochem/physiol Actions

Quipazine belongs to the class of psychedelics and acts as a serotonin/5-hydroxytryptamine-2A/C receptor agonist. It also acts as an inhibitor of prolactin.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P301 + P310 + P330

Hazard Classifications

Acute Tox. 3 Oral

저장 등급

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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A novel 5-HT(2A) receptor antagonist exhibits antidepressant-like effects in a battery of rodent behavioural assays: approaching early-onset antidepressants.

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Collective evidence suggests that inhibition of neuronal 5-hydroxytryptamine type 2A (5-HT(2A)) receptors contributes to the assuagement of depression-like behaviour in rodents. The present study evaluated the antidepressant-like effect of the 5-((4-benzo [alpha] isothiazol-3-yl) piperazin-1-yl) methyl)-6-chloroindolin-2-one (BIP-1), a compound having affinity

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British journal of pharmacology, 128(3), 530-542 (1999-10-12)

1. The effects of injections i.c.v. of quipazine, (2 micromol kg-1) and 1-(2,5-di-methoxy-4-iodophenyl)-2-aminopropane (DOI; 2 micromol kg-1) on renal sympathetic and phrenic nerve activity, mean arterial blood pressure (MAP) and heart rate were investigated in alpha-chloralose anaesthetized rats pretreated with

Sensory feedback modulates quipazine-induced stepping behavior in the newborn rat.

Michele R Brumley et al.

Behavioural brain research, 229(1), 257-264 (2012-01-18)

Research has shown that sensory feedback modulates locomotor behavior in intact as well as spinal adult animals. Here we examined if locomotor activity ("stepping") in newborn rats is influenced by cutaneous and proprioceptive feedback. One-day-old rats were treated with the

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국제 무역 품목 번호

SKU	GTIN
Q1004-250MG	04061836687694
Q1004-50MG	04061832084374