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PLA0108

Rabbit anti-DDB1 Antibody, Affinity Purified

Name: Rabbit anti-DDB1 Antibody, Affinity Purified
Brand: SIGMA

Powered by Bethyl Laboratories, Inc.

동의어(들):

127kDa, DDB p127 subunit, DDBA, DNA damage-binding protein a, Damage-specific DNA-binding protein 1, HBV X-associated protein 1, UV-DDB 1, UV-DDB1, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1, XAP-1, XAP1, XPCE, XPE, XPE-BF, XPE-binding factor, damage-specific DNA binding protein 1, damage-specific DNA binding protein 1 (127kD), xeroderma pigmentosum group E-complementing protein

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제품정보 (DICE 배송 시 비용 별도)

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, IP, WB

Citations:

기술 서비스

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도움 문의

속성

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

concentration

0.2 mg/mL

technique(s)

immunohistochemistry: 1:500- 1:2,000, immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:1,000- 1:10,000

accession no.

Q13289

UniProt accession no.

Q16531

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... DDB1(1642)

설명

Immunogen

The epitope recognized by PLA0108 maps to a region between residue 1100 and the C-terminus (residue 1140) of human damage-specific DNA binding protein 1 using the numbering given in TrEMBL entry Q13289 (GeneID 1642).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c