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Merck

P8908

Prostaglandin E1

synthetic, powder, BioReagent, suitable for cell culture

동의어(들):

(11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid, Alprostadil, PGE1

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C20H34O5
CAS 번호:
Molecular Weight:
354.48
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
EC Number:
212-017-2
Beilstein/REAXYS Number:
5294062
MDL number:
eCl@ss:
42020658
Biological source:
synthetic
Form:
powder
Assay:
≥98% (HPLC)
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biological source

synthetic

Quality Level

product line

BioReagent

assay

≥98% (HPLC)

form

powder

potency

0.25-100 ng/mL

technique(s)

cell culture | mammalian: suitable

solubility

acetone: 10 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

General description

Prostaglandin E1 (PGE1) is a vasodilator.

Application

Prostaglandin E1 may be used in cell culture to protect human umbilical vein endothelial cells (HUVEC) from injury induced by hydrogen peroxide.

Biochem/physiol Actions

Prostaglandin E1 (PGE1) aids in the relaxation of corporal cavernosal tissue. It helps to preserve the patency of the ductus arteriosus. It is used to treat erectile dysfunction (ED).

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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문서 라이브러리 방문



Vasculogenic Erectile Dysfunction
Vascular Medicine: A Companion to Braunwald's Heart Disease, 341-348 (2013)
David Furman et al.
Nature medicine, 23(2), 174-184 (2017-01-17)
Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear. Inflammasomes can drive chronic inflammation in the context of an infectious disease or cellular stress, and they trigger the
Corticotrophins, corticosteroids, and prostaglandins
Side Effects of Drugs Annual, 32, 723-733 (2010)



국제 무역 품목 번호

SKUGTIN
P8908-10MG04061834402053