주요 문서

모든 문서 보기

O3639

Ondansetron hydrochloride dihydrate

Name: Ondansetron hydrochloride dihydrate
Brand: SIGMA

≥98% (HPLC), powder, 5-HT₃serotonin receptor antagonist

동의어(들):

1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride, GR 38032F

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

보기 변경

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₈H₁₉N₃O · HCl · 2H₂O

CAS 번호:

103639-04-9

Molecular Weight:

365.85

UNSPSC Code:

12352200

PubChem Substance ID:

329818907

NACRES:

NA.32

MDL number:

MFCD00374371

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Storage condition:

desiccated

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

속성

제품 이름

Ondansetron hydrochloride dihydrate, ≥98% (HPLC), powder

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white

solubility

H₂O: >5 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].[H]O[H].[H]O[H].Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C

InChI

1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

InChI key

VRSLTNZJOUZKLX-UHFFFAOYSA-N

Gene Information

human ... HTR3A(3359)

설명

Application

Ondansetron hydrochloride dihydrate has been used as a 5-HT₃ antagonist to attenuate rostro ventromedial medulla (RVM)/cholecystokinin (CCK)-induced mechanical hypersensitivity and to block the effects of trichostatin A (TSA) on 5-HT₃ protein.

Biochem/physiol Actions

5-HT₃serotonin receptor antagonist

Ondansetron, (3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl) methyl] 1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride dehydrate acts as a selective 5-hydroxytryptamine type 3 (5-HT3) serotonin receptor antagonist. It is used as an antiemetic to control nausea and vomiting associated with chemotherapy and radiotherapy.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Still not finding the right product?

Explore all of our products under

pictograms

GHS06,GHS05,GHS09

signalword

Danger

hcodes

H301,H318,H410

pcodes

P264 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P391

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Global experience with ondansetron and future potential.

Butcher ME

Oncology, 50(3), 191-197 (1993)

Sleep Deprivation-Induced Blood-Brain Barrier Breakdown and Brain Dysfunction are Exacerbated by Size-Related Exposure to Ag and Cu Nanoparticles. Neuroprotective Effects of a 5-HT3 Receptor Antagonist Ondansetron.

Aruna Sharma et al.

Molecular neurobiology, 52(2), 867-881 (2015-07-03)

Military personnel are often subjected to sleep deprivation (SD) during combat operations. Since SD is a severe stress and alters neurochemical metabolism in the brain, a possibility exists that acute or long-term SD will influence blood-brain barrier (BBB) function and

Alcohol-induced serotonergic modulation: the role of histone deacetylases

Agudelo M

Alcohol, 46(7), 635-642 (2012)

모든 관련된 서류 보기

국제 무역 품목 번호

SKU	GTIN
O3639-10MG	04061834227687
O3639-50MG	04061833273319