M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine
≥98%
동의어(들):
8-Methoxymethyl-IBMX
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C12H18N4O3
CAS 번호:
Molecular Weight:
266.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Quality Level
assay
≥98%
form
solid
solubility
ethanol: 10 mg/mL
SMILES string
O=C1C(N=C(COC)N2)=C2N(CC(C)C)C(N1C)=O
InChI
1S/C12H18N4O3/c1-7(2)5-16-10-9(11(17)15(3)12(16)18)13-8(14-10)6-19-4/h7H,5-6H2,1-4H3,(H,13,14)
InChI key
NBLBCGUCPBXKOV-UHFFFAOYSA-N
Gene Information
human ... PDE1A(5136), PDE1B(5153)
Biochem/physiol Actions
Selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase I (PDE1).
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Methylxanthine inhibitors of phosphodiesterases.
J N Wells et al.
Methods in enzymology, 159, 489-496 (1988-01-01)
Haruka Kogiso et al.
International journal of molecular sciences, 21(6) (2020-03-18)
In Ts1Rhr, a Down syndrome model mouse, the airway ciliary beatings are impaired; that is, decreases in ciliary beat frequency (CBF) and ciliary bend angle (CBA, an index of ciliary beat amplitude)). A resumption to two copies of the Pcp4
Haruka Kogiso et al.
International journal of molecular sciences, 19(3) (2018-03-03)
Sei-hai-to (TJ-90, Qing Fei Tang), a Chinese traditional medicine, increases ciliary beat frequency (CBF) and ciliary bend angle (CBA) mediated via cAMP (3',5'-cyclic adenosine monophosphate) accumulation modulated by Ca2+-activated phosphodiesterase 1 (PDE1A). A high concentration of TJ-90 (≥40 μg/mL) induced
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| M2547-25MG | 04061832898919 |
| M2547-5MG | 04061832898926 |