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Merck

M1547

Sigma-Aldrich

Metronidazole

BioXtra

동의어(들):

2-Methyl-5-nitroimidazole-1-ethanol

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C6H9N3O3
CAS 번호:
443-48-1
Molecular Weight:
171.15
Beilstein:
611683
EC Number:
207-136-1
MDL number:
MFCD00009750
UNSPSC 코드:
51282808
PubChem Substance ID:
24896667
NACRES:
NA.76

주요 문서

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도움 문의

제품 라인

BioXtra

Quality Level

200

불순물

≤0.2% Total Impurities

무기 잔류물

≤0.1%

색상

white to light yellow

mp

159-161 °C (lit.)

solubility

acetic acid: 0.1 M, clear, colorless to yellow

음이온 미량물

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

양이온 미량물

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Na: ≤0.01%
Pb: ≤0.001%
Zn: ≤0.0005%

항생제 활성 스펙트럼

Gram-negative bacteria
parasites

동작 모드

DNA synthesis | interferes

저장 온도

2-8°C

SMILES string

CC1=NC=C([N+]([O-])=O)N1CCO

InChI

1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3

InChI key

VAOCPAMSLUNLGC-UHFFFAOYSA-N

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관련 카테고리

일반 설명

Chemical structure: imidazole

애플리케이션

Metronidazole is used to study DNA damage and repair and has been found to induce the gene transfer agent VSH-1 in Brachyspira hyodysenteriae. It is commonly used for treatment of periodontitis and is used in bioavailability studies.

생화학적/생리학적 작용

Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form. Reduced metronidazole covalently binds to DNA which disrupts its helical structure, induces DNA strand breaks and inhibits bacterial nucleic acid synthesis. Bacterial cell death results.

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H340,H350,H373

Hazard Classifications

Carc. 1B - Muta. 1B - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SLBQ9074V
SLBQ4358V
071M1445V
106K0046
033K14732

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