E6758
Ethylenediaminetetraacetic acid
anhydrous, crystalline, BioReagent, suitable for cell culture
동의어(들):
(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS 번호:
Molecular Weight:
292.24
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
39030907
UNSPSC Code:
12161700
EC Number:
200-449-4
MDL number:
Beilstein/REAXYS Number:
1716295
grade
anhydrous
product line
BioReagent
assay
≥98.5%
form
crystalline
reaction suitability
reagent type: chelator
technique(s)
cell culture | mammalian: suitable
pH
2.5 (23 °C, 10 g/L)
mp
250 °C (dec.) (lit.)
solubility
3 M NaOH: 100 mg/mL
density
1.46 g/cm3 at 20 °C
cation traces
C: 40.7-41.5%, N: 9.3-9.8%
SMILES string
OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
InChI
1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
InChI key
KCXVZYZYPLLWCC-UHFFFAOYSA-N
Application
Ethylenediaminetetraacetic acid has been used:
- as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
- as a medium component in the hepatic stellate cell (HSCs) culture
- as a component of homogenization buffer for protein extraction from eye tissues
- for stopping benzonase reaction in lysis buffer
Biochem/physiol Actions
Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.
signalword
Warning
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
target_organs
Respiratory Tract
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation
wgk
WGK 3
프로토콜
TE Buffer; Elution Buffer; 10x Ligation Buffer; 0.5 M PIPES Buffer; Inoue Transformation Buffer
Intracellular BH3 Profiling Reveals Shifts in Antiapoptotic Dependency in Human B Cell Maturation and Mitogen-Stimulated Proliferation
Dai J and Luftig MA
Journal of Immunology, ji1701473-ji1701473 (2018)
Protein Expressions of the Small GTPase Rho Proteins in Pterygial Tissue and Leukocytes of Patients with Pterygium
Saracaloglu A, et al.
Proceedings, 2(25), 1571-1571 (2018)
Analysis of Direct Interaction between Viral DNA-binding Proteins by Protein Pull-down Co-immunoprecipitation Assay
Lechuga A, et al.
Bio-protocol, 8(1), 1571-1571 (2018)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| E6758-100G | 04061835544592 |
| E6758-500G | 04061835544608 |