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D4007

5,5-Diphenylhydantoin

≥98%

동의어(들):

5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C15H12N2O2
CAS 번호:
57-41-0
Molecular Weight:
252.27
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
24278370
EC Number:
200-328-6
Beilstein/REAXYS Number:
384532
MDL number:
MFCD00005264
Assay:
≥98%
Form:
powder
Quality level:
100
기술 서비스
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도움 문의

Quality Level

100

assay

≥98%

form

powder

mp

293-295 °C (lit.)

solubility

DMSO: soluble

SMILES string

O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3

InChI

1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)

InChI key

CXOFVDLJLONNDW-UHFFFAOYSA-N

Gene Information

human ... CNR1(1268), CNR2(1269), CYP2C9(1559), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Faah(29347), Scn1a(81574), Scnn1g(24768), Slc6a1(79212)

General description

5,5-Diphenylhydantoin is an anticonvulsant, which is used to treat tonic-clonic seizures, complex partial seizures and neurosurgical related seizures. It induces osteoblast proliferation and differentiation. 5,5-Diphenylhydantoin used to treat epilepsy. It reduces the hyperexcitability of tissues and may be associated with cerebellar atrophy.

Application

5,5-Diphenylhydantoin has been used for phenytoin treatment. It has also been used to slow down or prevent mesoendoderm cell migration.

Biochem/physiol Actions

Anticonvulsant.
Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
088K0802
S60947
053K3672
124F0177
121K1518

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문서 라이브러리 방문

Advanced Therapy in Epilepsy (2009)
Phenytoin activates SMAD3 phosphorylation and periostin expression in drug-induced gingival enlargement
Kim SS, et al.
Histology and Histopathology, 33(12), 1287-1298 (2018)
In Vitro Micropatterned Human Pluripotent Stem Cell Test (muP-hPST) for Morphometric-Based Teratogen Screening
Xing J, et al.
Scientific Reports, 7(1), 8491-8491 (2017)
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국제 무역 품목 번호

SKUGTIN
D4007-100G04061833563793
D4007-5G04061833563809