D3506
Sodium diethyldithiocarbamate trihydrate
≥97% (perchloric acid titration), chelating agent, powder or crystals
동의어(들):
Cupral, Diethyldithiocarbamic acid sodium salt
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(C2H5)2NCSSNa · 3H2O
CAS 번호:
Molecular Weight:
225.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
205-710-6
MDL number:
Beilstein/REAXYS Number:
3920507
제품 이름
Sodium diethyldithiocarbamate trihydrate,
vapor density
5.9 (vs air)
Quality Level
assay
≥97% (perchloric acid titration)
form
powder or crystals
mp
95-98.5 °C (lit.)
solubility
water: 1 g/10 mL, slightly hazy
storage temp.
room temp
SMILES string
[H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
InChI
1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
InChI key
WWGXHTXOZKVJDN-UHFFFAOYSA-M
Application
Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues.
Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Biochem/physiol Actions
Inhibits induction of macrophage nitric oxide synthase.
Features and Benefits
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Dopamine, Norepinephrine and Epinephrine Synthesis page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
May form insoluble oxidation products in storage. Sensitivity in colorimetric copper determination not usually affected.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
문서
Discover Bioactive Small Molecules for ADME/Tox
관련 콘텐츠
ADME/Tox를 위한 생체 활성 저분자
P E James et al.
Advances in experimental medicine and biology, 454, 181-187 (1999-01-16)
Although nitric oxide (NO) is a central mediator during endotoxin-induced sepsis, direct detection of tissue NO in vivo, has until recently been difficult, and techniques have relied on indirect measurement of bi-products in blood or invasive technology. We have utilized
Y Suzuki et al.
Free radical research, 28(3), 293-299 (1998-08-04)
To detect nitric oxide (NO) in the rat brain during lipopolysaccharide (LPS)-induced sepsis, electron paramagnetic resonance (EPR) was employed with the NO trapping technique, using an iron and N,N-diethyldithiocarbamate (DETC) complex. An X-band (about 9.5 GHz) EPR system detected a
Tianhui Liu et al.
British journal of pharmacology, 175(24), 4480-4495 (2018-09-29)
Diethyldithiocarbamate (DDC) is a major metabolite of disulfiram that is a potential drug for alcoholism treatment. In the present study, we attempted to explore the possible effect of DDC on non-alcoholic fatty liver disease (NAFLD) and related fibrosis in vivo.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| D3506-100G | 04061833563212 |
| D3506-500G | 04061833563236 |