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Merck

C7602

L-Cystine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

동의어(들):

(R,R)-3,3′-Dithiobis(2-aminopropionic acid)

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS 번호:
Molecular Weight:
240.30
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-296-3
MDL number:
Beilstein/REAXYS Number:
1728094
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제품 이름

L-Cystine, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

Quality Level

agency

meets EP testing specifications

product line

BioXtra

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

>240 °C (dec.) (lit.)

solubility

1 M HCl: 100 mg/mL

application(s)

peptide synthesis

SMILES string

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

Application

L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids.
L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development.

Biochem/physiol Actions

Cystinuria is characterized with renal transport and excretion of L-Cystine. Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells.


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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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문서 라이브러리 방문


문서

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures


Studies on Analogues of L-Cysteine and L-Cystine
Austin S and Leif G
Blood (2018)
Mutation of Ataxia?Telangiectasia Mutated is Associated with Dysfunctional Glutathione Homeostasis in Cerebellar Astroglia
Andrew Campbell
Glia, 64(2), 227-239 (2016)
Transport Interaction of t-Cystine and L-Glutamate in Human Diploid
Fibroblasts in Culture
Shiro Bannai and Emi Kitamur
The Journal of Biological Chemistry, 255(6), 2372- 2376 (1980)



국제 무역 품목 번호

SKUGTIN
C7602-25G04061833513101
C7602-100G04061833513064
C7602-10MG04061833513071
C7602-1KG04061833513088