C2020

α-Cyano-4-hydroxycinnamic acid

Name: α-Cyano-4-hydroxycinnamic acid
Brand: SIGMA

≥98% (TLC), powder, monocarboxylic acid transport inhibitor

동의어(들):

α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA

로그인조직 및 계약 가격 보기

크기 선택

제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

HOC₆H₄CH=C(CN)CO₂H

CAS 번호:

28166-41-8

Molecular Weight:

189.17

Beilstein:

3271427

EC Number:

248-879-1

MDL number:

MFCD00004204

UNSPSC 코드:

12352106

PubChem Substance ID:

24892459

NACRES:

NA.77

주요 문서

모든 문서 보기

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

제품 이름

α-Cyano-4-hydroxycinnamic acid, ≥98% (TLC), powder

Quality Level

300

분석

≥98% (TLC)

양식

powder

색상

yellow

mp

245-250 °C (lit.)

solubility

H₂O: slightly soluble
methanol: water: soluble
polar organic solvents: soluble

저장 온도

2-8°C

SMILES string

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

InChI key

AFVLVVWMAFSXCK-VMPITWQZSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

α-Cyano-4-hydroxycinnamic acid has been used to block monocarboxylate transporters.

α-Cyano-4-hydroxycinnamic acid is a useful hydrophobic matrix solution for matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Antibiotics, peptide nucleic acids (a new class of DNA mimics), and proteins with masses as high as 66,000 Da have been successfully analyzed by using this as a matrix solution.

생화학적/생리학적 작용

α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC₅₀ of 2.4 mM).

픽토그램

GHS07

신호어

Warning

유해 및 위험 성명서

H317

예방조치 성명서

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Glucose catabolism in African trypanosomes. Evidence that the terminal step is catalyzed by a pyruvate transporter capable of facilitating uptake of toxic analogs.

J P Barnard et al.

The Journal of biological chemistry, 268(5), 3654-3661 (1993-02-15)

The protozoan parasite Trypanosoma brucei derives its metabolic energy exclusively from a unique type of glycolysis in which pyruvate derived from glucose catabolism is released into the host bloodstream. In this study, this terminal metabolic step has been examined in

L-Lactate Promotes Adult Hippocampal Neurogenesis

Lev-Vachnish Y, et al.

Frontiers in Neuroscience, 13 (2019)

Formulation of matrix solutions for use in matrix-assisted laser desorption/ionization of biomolecules.

E T Sze et al.

Journal of the American Society for Mass Spectrometry, 9(2), 166-174 (1998-07-29)

We report a simple method for converting solid matrices into useful matrix solutions for matrix-assisted laser desorption/ionization (MALDI). This method is based on the dissolution of the solid matrix in a liquid support of low volatility such as glycerol. An

Transport characteristics of the apical anion exchanger of rabbit cortical collecting duct beta-cells.

C Emmons

The American journal of physiology, 276(4 Pt 2), F635-F643 (1999-04-13)

To functionally characterize transport properties of the apical anion exchanger of rabbit beta-intercalated cells, the mean change in anion exchange activity, dpHi/dt (where pHi is intracellular pH), was measured in response to lumen Cl- replacement with gluconate in perfused cortical

Quantitative analysis of antibiotics by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Y C Ling et al.

Rapid communications in mass spectrometry : RCM, 12(6), 317-327 (1998-04-16)

Comparative studies of the matrix-assisted laser desorption/ionization (MALDI) of 30 antibiotics were made using alpha-cyano-4-hydroxycinnamic acid (HCCA), 2,5-dihydroxybenzoic acid (DHB), 5,10,15,20-tetrakis(4-hydroxyphenyl)-21H,23H-porphyrin and meso-tetra(N-methyl-4-pyridyl)porphyrin matrices. Most antibiotics generated intense protonated molecules in HCCA and DHB matrices, and sodium or potassium adduct

모든 관련된 서류 보기

문서

Aerobic Glycolysis and the Warburg Effect

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

α-Cyano-4-hydroxycinnamic acid

≥98% (TLC), powder, monocarboxylic acid transport inhibitor

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

Quality Level

분석

양식

색상

mp

solubility

저장 온도

SMILES string

InChI

InChI key

관련 카테고리

설명

애플리케이션

생화학적/생리학적 작용

안전성 정보

픽토그램

신호어

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Storage Class Code

WGK

Flash Point (°F)

Flash Point (°C)

개인 보호 장비

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

관련 참고 프로토콜

문서

관련 콘텐츠

기술 서비스