주요 문서

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A6106

Aprotinin

Name: Aprotinin
Brand: SIGMA

BioUltra, 3-8 TIU/mg solid, powder, ≥98% (SDS-PAGE), suitable for inhibition assay

동의어(들):

BPTI, Bovine pancreatic trypsin inhibitor, Trasylol, Trypsin inhibitor (basic)

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

보기 변경

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₂₈₄H₄₃₂N₈₄O₇₉S₇

CAS 번호:

9087-70-1

Molecular Weight:

6511.44

UNSPSC Code:

12352204

NACRES:

NA.77

EC Number:

232-994-9

MDL number:

MFCD00130541

eCl@ss:

32190102

기술 서비스

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도움 문의

속성

제품 이름

Aprotinin from bovine lung, BioUltra, 3-8 TIU/mg solid, ≥98% (SDS-PAGE)

biological source

bovine lung

Quality Level

300

product line

BioUltra

assay

≥98% (SDS-PAGE)

form

powder

specific activity

3-8 TIU/mg solid

mol wt

~6,500

technique(s)

inhibition assay: suitable

solubility

H₂O: 5 mg/mL, clear to very slightly hazy

UniProt accession no.

P00974

storage temp.

2-8°C

SMILES string

S1SCC2NC(=O)CNC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C5NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C9N(CCC9)C(=O)CNC(=O)C(NC(=O)C(NC(=O)C%11N(CCC%11)C(=O

InChI

1S/C284H432N84O79S7/c1-21-144(9)222-271(439)337-174(68-46-105-309-282(300)301)239(407)340-187(120-160-77-85-164(374)86-78-160)251(419)341-185(116-156-55-29-24-30-56-156)250(418)342-188(121-161-79-87-165(375)88-80-161)252(420)346-191(123-208(291)378)246(41

InChI key

ZPNFWUPYTFPOJU-UHFFFAOYSA-N

Gene Information

cow ... PTI(404172)

설명

Application

Aprotinin is largely used as an inhibitor of trypsin.

Biochem/physiol Actions

Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.

Preparation Note

A further purification of A1153 to yield a product with slightly higher activity and purity

Other Notes

One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of N-alpha-benzoyl-DL-arginine p-nitroanilide per minute at pH 7.8 and 25°C. Another commonly used unit is the KIU, with 1 TIU = 1,300 KIU.

One trypsin inhibitor unit (TIU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 μmole of N-α-benzoyl-DL-arginine p-nitroanilide (BAPNA) per min at pH 7.8 at 25 °C.

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저장 등급

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시험 성적서(COA)

Lot/Batch Number

107K7728

107K7727

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문서 라이브러리 방문

프로토콜

Enzymatic Assay of Aprotinin

Objective: To standardize a procedure for the enzymatic assay of Aprotinin.

문서

Aprotinin

While aprotinin and bovine pancreatic trypsin inhibitor (BPTI) are the same protein sequence, the term aprotinin is typically used when describing the protein derived from bovine lung.

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모든 관련된 서류 보기

국제 무역 품목 번호

SKU	GTIN
A6106-1MG	04061826696149
A6106-100MG	04061833228340
A6106-25MG	04061833228357

주요 문서

Aprotinin

BioUltra, 3-8 TIU/mg solid, powder, ≥98% (SDS-PAGE), suitable for inhibition assay

크기 선택

제품정보 (DICE 배송 시 비용 별도)

제품 이름

biological source

Quality Level

product line

assay

form

specific activity

mol wt

technique(s)

solubility

UniProt accession no.

storage temp.

SMILES string

InChI

InChI key

Gene Information

Application

Biochem/physiol Actions

Preparation Note

Other Notes

Still not finding the right product?

안전성 정보

저장 등급

wgk

flash_point_f

flash_point_c

ppe

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