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Merck

G0876

β-Glucuronidase from Helix pomatia

Type H-2, aqueous solution, ≥85,000 units/mL

동의어(들):

β-D-Glucuronide glucuronosohydrolase

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크기 선택

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
EC 번호:
MDL number:
Specific activity:
≥85,000 units/mL
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type

Type H-2

Quality Level

form

aqueous solution

specific activity

≥85,000 units/mL

secondary activity

≤7,500 units/mL sulfatase

shipped in

wet ice

storage temp.

2-8°C

Application

New Technical Article Comparing Performance of Different Enzymes
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine

Biochem/physiol Actions

Used for the hydrolysis of glucuronide conjugates in urinary metabolite analysis

Physical form

Aqueous solution in ~1.0 M ammonium sulfate with 3 mM sodium azide as preservative.

Analysis Note

Many β-glucuronidases derived from mollusks also contain sulfatase activity.

Other Notes

One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 5.0 (30 min assay).
Sulfatase Unit Definition: One unit of sulfatase will hydrolyze 1.0 μmole p-nitrocatechol sulfate per hr at pH 5.0 at 37 °C.


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

저장 등급

10 - Combustible liquids

wgk

WGK 1



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문


프로토콜

Enzymatic assay protocol for β-Glucuronidase from Helix Pomatia and Bovine Liver aids laboratory personnel in following procedures.

문서

β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS.

관련 콘텐츠


Tien-Jen Lin et al.
International journal of environmental research and public health, 15(7) (2018-07-11)
The measurement of polycyclic aromatic hydrocarbons (PAH) in ambient air is quite difficult to perform. Using urine biomarkers of PAH such as 2-naphthol is one approach to this problem. This study explored the association between urine 2-naphthol levels and allergic
Yanyan Zhang et al.
Environmental pollution (Barking, Essex : 1987), 184, 515-522 (2013-11-02)
Daily dietary and inhalation exposures to 16 parent polycyclic aromatic hydrocarbons (PAHs) and urinary excretion of 13 monohydroxy metabolites (OHPAHs) were monitored for 12 non-smoking university students in Beijing, China, during a controlled feeding experiment. The relationship between the urinary
Ke Wang et al.
Microbiology (Reading, England), 150(Pt 10), 3327-3339 (2004-10-08)
In Saccharomyces cerevisiae, PRS genes comprise a family of five paralogous genes. Previously, it has been shown that in the cell the gene products are organized into two interacting complexes, one of which is a heterodimer and the other a



국제 무역 품목 번호

SKUGTIN
G0876-25ML04061833624357
G0876-5X25ML04061833624395
G0876-10ML04061838087423
G0876-1ML04061833624333
G0876-2ML04061833624371
G0876-5ML04061833624388