73677
4-Nitrophenyl β-D-glucuronide
β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test
동의어(들):
4-Nitrophenyl-β-D-glucopyranosiduronic acid, PNPG
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C12H13NO9
CAS 번호:
Molecular Weight:
315.23
Beilstein:
1438576
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32
제품 이름
4-Nitrophenyl β-D-glucuronide, ≥99.0% (TLC)
Quality Level
분석
≥99.0% (TLC)
양식
powder or crystals
광학 활성
[α]20/D −102±3°, c = 1% in ethanol
불순물
≤0.05% free 4-nitrophenol
≤7% water
solubility
H2O: 0.1 g/mL, clear, faintly yellow
적합성
suitable as substrate for β-glucuronidase test
저장 온도
−20°C
SMILES string
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O
InChI
1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1
InChI key
QSUILVWOWLUOEU-GOVZDWNOSA-N
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일반 설명
Chromogenic substrate for β-glucuronidase (GUS) gene detection.
애플리케이션
4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Bizonn A, et al.
Przegla?d Lekarski, 71(11), 581-584 (2014)
Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Pabba J, et al.
Helvetica Chimica Acta, 89(4), 635-666 (2006)
Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
El-Arab AME, et al.
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
H Iwabuchi et al.
Journal of chromatography, 414(1), 139-148 (1987-02-20)
Molecular-secondary-ion mass spectrometry (SIMS) is a suitable method for the analysis of nonvolatile substances such as conjugated metabolites of drugs. We have developed a simple method for the direct SIMS measurement of conjugates following thin-layer chromatography without any extraction procedure.
Positive and negative liquid secondary ion mass spectrometry of chloro- and nitrophenylglucuronides.
P P Wickramanayake et al.
Biomedical mass spectrometry, 12(3), 127-133 (1985-03-01)
Mass spectra of a series of chloro- and nitrophenylglucuronides by liquid secondary ion (LSI) mass spectrometry were obtained. In the positive ion mode class characteristic fragmentations and adduct ions are observed only in the presence of alkali salt additives. No
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