description
non-ionic
Quality Level
form
liquid
mol wt
~603.0 g/mol
refractive index
n20/D 1.492
CMC
0.08 mM (20-25°C)
transition temp
cloud point 63-67 °C
density
1.06 g/mL at 20 °C
anion traces
chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤1000 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤1000 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
HLB
13
SMILES string
O(CCO)c1ccc(cc1)C(CC(C)(C)C)(C)C
InChI
1S/C16H26O2/c1-15(2,3)12-16(4,5)13-6-8-14(9-7-13)18-11-10-17/h6-9,17H,10-12H2,1-5H3
InChI key
JYCQQPHGFMYQCF-UHFFFAOYSA-N
General description
IGEPAL® CA-630 is a nonionic, non-denaturing detergent suitable for solubilization, isolation and purification of membrane protein complexes. It is chemically indistinguishable from Nonidet P-40.
Application
IGEPAL® CA-630 has been used:
- In phosducin co-precipitation assay for pull down of Epitope-Tagged HAGγ1 and HAGγ1C71S
- As a component of lysis buffer for cell culture and sample preparation for MAPK (mitogen-activated protein kinases) analysis, Immunoblotting
- In the extraction of cells in Oil Red O staining procedure to visualise lipid formation in cells during adipogenesis
- As a component of lysis buffer containing Tris-HCl, NaCl and EDTA for immunoblotting experiment
Analysis Note
Chemically indistinguishable from Nonidet P-40, which is no longer commercially available.
Other Notes
Nonionic, non-denaturing detergent
Legal Information
IGEPAL is a registered trademark of Solvay
Nonidet is a trademark of Shell Chemical Co.
Disclaimer
May become turbid on storage; a clear product can be obtained on heating to 40°C.
May develop turbidity or sediment during storage. A clear liquid can be obtained on heating to 40°C.
signalword
Danger
저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
483.8 °F - closed cup
flash_point_c
251 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2
MEK?ERK and heparin-susceptible signaling pathways are involved in cell-cycle entry of the wound edge retinal pigment epithelium cells in the adult newt.
Yoshikawa T, et al.
Pigment Cell & Melanoma Research, 25(1), 66-82 (2012)
Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors.
Frontiers in Molecular Neuroscience, 11, 16-16 (2018)
Selective mutations in estrogen receptor alpha' s D-domain alters nuclear translocation and non-ERE gene regulatory mechanisms.
Burns K A, et al.
The Journal of Biological Chemistry, jbc-M110 (2011)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 56741-250ML-F | 04061832589305 |
| 56741-50ML-F | 04061832589312 |


