주요 문서

모든 문서 보기

42602

Propionyl-L-carnitine

Name: Propionyl-L-carnitine
Brand: SIGMA

≥94.0% (HPLC), suitable for LC/MS

동의어(들):

(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

보기 변경

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₀H₁₉NO₄

CAS 번호:

20064-19-1

Molecular Weight:

217.26

UNSPSC Code:

12352209

PubChem Substance ID:

329756246

NACRES:

NA.26

MDL number:

MFCD00870024

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

속성

제품 이름

Propionyl-L-carnitine, ≥94.0% (HPLC)

Quality Level

100

assay

≥94.0% (HPLC)

form

powder or crystals

optical activity

[α]/D -23±3°, c = 1 in H₂O

technique(s)

LC/MS: suitable

impurities

≤10% water (calcd. from elemental analysis)

color

white to off-white

storage temp.

2-8°C

SMILES string

[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O

InChI

1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1

InChI key

UFAHZIUFPNSHSL-MRVPVSSYSA-N

설명

General description

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

Application

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem/physiol Actions

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

Still not finding the right product?

Explore all of our products under

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

도움이 필요하시면 연락하세요. 고객 지원 부서

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine.

Santica M Marcovina et al.

Translational research : the journal of laboratory and clinical medicine, 161(2), 73-84 (2012-11-10)

Mitochondria play important roles in human physiological processes, and therefore, their dysfunction can lead to a constellation of metabolic and nonmetabolic abnormalities such as a defect in mitochondrial gene expression, imbalance in fuel and energy homeostasis, impairment in oxidative phosphorylation

Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism.

M J Cipolla et al.

Journal of vascular surgery, 29(6), 1097-1103 (1999-06-09)

The vasoactive effects of propionyl-L-carnitine (PLC) on human arteries, including endothelial and smooth muscle cell influences, were studied. Small (less than 200 microm) subcutaneous fat arteries (n = 19), obtained from human patients undergoing vascular surgery, were dissected and mounted

Effect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease.

William R Hiatt et al.

Journal of cardiopulmonary rehabilitation and prevention, 31(2), 125-132 (2010-09-24)

Exercise training is established for the treatment of peripheral artery disease; however the additional benefit of pharmacologic therapy with exercise has not been studied. This trial tested the hypothesis that propionyl-L-carnitine (PLC), in combination with monitored home-based exercise training, would

모든 관련된 서류 보기

국제 무역 품목 번호

SKU	GTIN
42602-50MG	04061833411308
42602-10MG	04061833380666