30200
L-Cystine
≥99.7% (TLC)
동의어(들):
(R,R)-3,3′-Dithiobis(2-aminopropionic acid)
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS 번호:
Molecular Weight:
240.30
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-296-3
MDL number:
Beilstein/REAXYS Number:
1728094
제품 이름
L-Cystine, ≥99.7% (TLC)
Quality Level
assay
≥99.7% (TLC)
form
powder or crystals
optical activity
[α]20/D −219±5°, c = 1% in 1 M HCl
ign. residue
≤0.1% (as SO4)
loss
≤0.1% loss on drying
color
white
mp
>240 °C (dec.) (lit.)
solubility
1 M HCl: 0.5 g/10 mL, clear, colorless
anion traces
chloride (Cl-): ≤500 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤6 mg/kg, Fe: ≤10 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤150 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
application(s)
peptide synthesis
SMILES string
N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
InChI
1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChI key
LEVWYRKDKASIDU-IMJSIDKUSA-N
Application
L-Cystine has been used to prepare stock solution which in turn is utilized for determining the L-cysteine and L-cystine in pharmaceutical preparations as well as in urine samples by using spectrofluorimetric flow injection method.
Biochem/physiol Actions
Cystine is required for the synthesis of glutathione that protects the cells from oxidative stress. A specific x(c)-cysteine/glutamate antiporter mediates cellular uptake of cysteine in exchange for glutamate. Inhibition of cysteine uptake induces toxicity in neuronal cells.
Other Notes
Preparation of N,N′-dibenzoyl-L-cystine, an efficient auxiliary for enantioselective reductions of ketones
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
K. Soai et al.
Journal of the Chemical Society. Chemical Communications, 413-413 (1984)
T H Murphy et al.
Neuron, 2(6), 1547-1558 (1989-06-01)
Glutamate binds to both excitatory neurotransmitter binding sites and a Cl(-)-dependent, quisqualate- and cystine-inhibited transport site on brain neurons. The neuroblastoma-primary retina hybrid cells (N18-RE-105) are susceptible to glutamate-induced cytotoxicity. The Cl(-)-dependent transport site to which glutamate and quisqualate (but
Journal of the Chemical Society. Chemical Communications, 801-801 (1987)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 30200-100G | 04061826665640 |
| 30200-25G | 04061826665657 |
| 30200-500G | 04061826665664 |