04260
N-Ethylmaleimide
purum p.a., ≥99.0% (HPLC)
동의어(들):
NEM
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C6H7NO2
CAS 번호:
Molecular Weight:
125.13
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
204-892-4
MDL number:
Beilstein/REAXYS Number:
112448
grade
purum p.a.
Quality Level
assay
≥99.0% (HPLC)
ign. residue
≤0.05%
bp
210 °C (lit.)
mp
43-46 °C
anion traces
chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤100 mg/kg, Na: ≤100 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg
storage temp.
2-8°C
SMILES string
CCN1C(=O)C=CC1=O
InChI
1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChI key
HDFGOPSGAURCEO-UHFFFAOYSA-N
Gene Information
human ... SLC6A3(6531), SLC6A4(6532)
Application
Reagent for the covalent modification of cysteine residues in proteins.
N-Ethylmaleimide has been used to measure low molecular weight thiols bound to plasma proteins.
Biochem/physiol Actions
Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
저장 등급
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
163.2 °F - closed cup
flash_point_c
72.9 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Plasma protein thiolation index (PTI) as a biomarker of thiol-specific oxidative stress in haemodialyzed patients.
Colombo G, et al.
Free Radical Biology & Medicine, 89, 443-451 (2015)
Koichi Tan-No et al.
International review of neurobiology, 85, 191-205 (2009-07-18)
Dynorphins, the endogenous opioid peptides derived from prodynorphin may participate not only in the inhibition, but also in facilitation of spinal nociceptive transmission. However, the mechanism of pronociceptive dynorphin actions, and the comparative potential of prodynorphin processing products to induce
Tatsuki Kurokawa et al.
Biochimica et biophysica acta, 1838(1 Pt B), 382-387 (2013-10-22)
Hv1 (also named, voltage-sensor only protein, VSOP) lacks an authentic pore domain, and its voltage sensor domain plays both roles in voltage sensing and proton permeation. The activities of a proton channel are intrinsic to protomers of Hv1, while Hv1
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 93598-100MG | 04061833282946 |
| 8048120100 | 04022536386492 |
| 8048120500 | 04022536386508 |
| 8048129050 | 04022536386515 |
| I29204-100G | 04061833848777 |
| I29204-1KG | 04061833848784 |
| 04260-25G-F | 04061838629302 |
| 04260-5G-F | 04061838629319 |