439134
Acetonitrile
≥99.9%, gradient grade, suitable for UV/Vis spectroscopy, HPLC
동의어(들):
Methyl cyanide, Anhydrous ACN, Dry MeCN
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3CN
CAS 번호:
Molecular Weight:
41.05
NACRES:
NA.03
PubChem Substance ID:
UNSPSC Code:
12190000
EC Number:
200-835-2
MDL number:
Beilstein/REAXYS Number:
741857
Assay:
≥99.9%
Grade:
gradient grade
Technique(s):
HPLC: suitable, UV/Vis spectroscopy: suitable
Bp:
81-82 °C (lit.)
Vapor pressure:
72.8 mmHg ( 20 °C)
제품 이름
Acetonitrile, suitable for HPLC, gradient grade, ≥99.9%
grade
gradient grade
Quality Level
vapor density
1.41 (vs air)
vapor pressure
72.8 mmHg ( 20 °C)
description
HPLC gradient analysis <= 0.5 mAU @254 nm, HPLC gradient analysis <= 3 mAU @ 210 nm, baseline drift at 210 nm <= 15 mAU
assay
≥99.9%
form
liquid
autoignition temp.
973 °F
purified by
sub-micron filtration
expl. lim.
16 %
technique(s)
HPLC: suitable, UV/Vis spectroscopy: suitable
impurities
≤0.0002% free alkali (as NH3), ≤0.001% free acid (as CH3COOH), ≤0.01% water (Karl Fischer), ≤0.5 ppb quinine fluor., 365 nm, ≤1 ppb quinine fluor., 254 nm
evapn. residue
<0.0002%
refractive index
n20/D 1.344 (lit.)
bp
81-82 °C (lit.)
mp
−45 °C (lit.)
solubility
water: soluble
density
0.786 g/mL at 25 °C (lit.)
λ
H2O reference
UV absorption
λ: 195 nm Amax: ≤0.12, λ: 200 nm Amax: ≤0.032, λ: 230 nm Amax: ≤0.0044
application(s)
food and beverages
format
neat
SMILES string
CC#N
InChI
1S/C2H3N/c1-2-3/h1H3
InChI key
WEVYAHXRMPXWCK-UHFFFAOYSA-N
General description
Acetonitrile (MeCN), an aliphatic nitrile, is a colorless liquid with a pleasant odor. It is widely used as a solvent and intermediate in organic syntheses. It is transparent to UV-visible light making it highly applicable in spectrophotometric and fluorimetric techniques. As MeCN has low viscosity, high elution strength and is highly miscible in water, it is utilized as a mobile phase component in many chromatographic techniques. Its infrared spectrum has been recorded. Synthesis of alkyl hydroperoxides in MeCN by alkane oxidation with hydrogen peroxide in the presence of iron complexes has been studied. The hydrogenation of MeCN to form ethylamine using Co–B amorphous alloy catalyst has been investigated.
Application
- Chromatographic Separation of Anthocyanins: Acetonitrile is a preferred solvent in high-performance liquid chromatography (HPLC) for the separation of anthocyanins and other phenolic compounds. Studies have explored the selectivity control of anthocyanin separation by replacing acetonitrile with methanol in the mobile phase, highlighting the solvent′s role in optimizing chromatographic conditions for improved resolution and detection sensitivity (Deineka et al., Journal of Analytical Chemistry, 2021).
- Peroxyoxalate Chemiluminescence Detection: Acetonitrile is used in peroxyoxalate chemiluminescence for the detection of α-amino acids. The solvent′s ability to form stable mixed solutions with water and ethyl acetate enhances the chemiluminescence reaction, allowing for sensitive and selective detection of amino acids in various samples. This application is essential for biochemical and clinical analyses (Kan et al., American Journal of Analytical Chemistry, 2020).
- Electrochemical Detection of DNA Modifications: Acetonitrile is utilized in electrochemical methods for detecting DNA modifications, such as 5-formyluracil. The solvent′s role in stabilizing the (2-benzimidazolyl) acetonitrile labeling reaction enhances the selectivity and sensitivity of detecting DNA modifications, which is crucial for genomic and biomedical research (Tang et al., Analytical Chemistry, 2021).
- Alternative Solvent in Chromatography: Research has investigated replacing acetonitrile with ethanol in reversed-phase HPLC for determining anthocyanins. This substitution aims to maintain chromatographic performance while reducing the environmental impact and costs associated with acetonitrile use. The findings demonstrate the feasibility of using ethanol as a greener alternative without compromising analytical quality (Deineka et al., Journal of Analytical Chemistry, 2023).
Packaging
M-Bottle for Solvents
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As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!
Preparation Note
Product filtered through a 0.2 μm filter
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
저장 등급
3 - Flammable liquids
flash_point_f
35.6 °F - closed cup
flash_point_c
2.0 °C - closed cup
프로토콜
A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.
H Haugen et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 73(2), 229-237 (2005-03-10)
This article deals with enzyme-induced biodegradation behavior of thermoplastic polyether-urethane (TPU). Porous scaffolds were processed by a new foaming method applied in hot pressing and injection molding. The scaffolds were subsequently gamma sterilized. The samples were incubated with cholesterol esterase
Infrared spectra of acetonitrile and acetonitrile-d3.
Pace EL and Noe LJ.
J. Chem. Phys., 49, 5317-5325 (1968)
Liquid phase hydrogenation of acetonitrile to ethylamine over the Co-B amorphous alloy catalyst.
Li H, et al.
J. Catal., 214(1), 15-25 (2003)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 439134-20L | 04061832245942 |
| 439134-4L | 04061837479021 |
| 439134-10L | 04061837287350 |
| 439134-18L | 04061837479007 |
| 439134-1L | 04061837479014 |
| 439134-2X10L | 04061837287398 |
| 439134-4X4L | 04061837479038 |